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- W4235512251 abstract "The effects of GABA and picrotoxin on the input resistance of the muscle of the earthworm, Pheretima communissima in Ringer solution and in solutions containing various foreign anions were observed. 1. Substitution of Cl- by I- and Br- reduced the input resistance and hyperpolarized the membrane. Although anions larger than chloride in hydrated size increased the input resistance, no change of the membrane potential was observed. 2. GABA reduced the input resistance of the membrane and picrotoxin increased it in Ringer solution. The dose-response curve for the changes of the input resistance under various concentrations of GABA shifted parallel-wise under treatment with picrotoxin. 3. In the presence of foreign anions which had larger hydration size than Br-, GABA reduced the input resistance. Picrotoxin did not, however, increase the input resistance when the solutions contained anions of smaller hydration size than ClO4-. 4. Reversal potential levels for the miniature inhibitory junction potential in various concentrations of chloride were measured. The change of the reversal potential levels produced by a tenfold change of chloride concentration was 25 mV." @default.
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- W4235512251 date "1969-11-01" @default.
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- W4235512251 title "Effects of γ-Aminobutyric Acid and Picrotoxin on the Permeability of the Longitudinal Muscle of the Earthworm to Various Anions" @default.
- W4235512251 doi "https://doi.org/10.1242/jeb.51.2.363" @default.
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