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- W4235637701 abstract "Aplastic anemia is an immune-mediated disorder where myeloid progenitors and pluripotent stem cells are severely diminished or absent in the bone marrow leading to pancytopenia Brodsky, R.A. and Jones, R.J. (2005). Aplastic anemia. Lancet 365, 1647–1656. The majority of the cases are idiopathic. Other causes include various drugs, infections, radiation, and other toxic exposures. It may present with signs and symptoms common in pancytopenia. Bleeding is the most common early symptom. Anemia may present with increasing weakness and shortness of breath. First-line therapy for aplastic anemia should include withdrawal of potentially offending agents and supportive measures (e.g., transfusion, antibiotics). Definitive therapy for aplastic anemia is either hematopoietic stem cell transplantation or immunosuppression." @default.
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- W4235637701 date "2014-01-01" @default.
- W4235637701 modified "2023-09-26" @default.
- W4235637701 title "Aplastic Anemia☆" @default.
- W4235637701 doi "https://doi.org/10.1016/b978-0-12-801238-3.04855-8" @default.
- W4235637701 hasPublicationYear "2014" @default.
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