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- W4235655372 abstract "The recent data about innate and adaptive immunity against neuroblastoma are described in the article. The era of neuroblastoma immunotherapy started since the evidence of anti-GD2 monoclonal antibodies efficiency. Nowadays monoclonal antibodies against GD2 are introduced into schemes of maintenance therapy for high-risk neuroblastoma patients. Developing of T-cells expressing chimeric antigen receptor (CAR-T cells) directed to membrane antigens is the perspective of neuroblastoma immunotherapy. PD1/PD-L1 blocking antibodies as immune checkpoint inhibitors have the theoretical evidence of potential effectiveness. Application of immunotherapeutic approaches in high-risk neuroblastoma patients together with conventional multimodal therapies requires further investigation." @default.
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- W4235655372 date "2019-02-01" @default.
- W4235655372 modified "2023-09-27" @default.
- W4235655372 title "NEUROBLASTOMA IMMUNOTHERAPY" @default.
- W4235655372 doi "https://doi.org/10.37469/0507-3758-2019-65-2-181-187" @default.
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