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- W4235697883 abstract "Oxidative radical CC couplings form CC bonds by using radical intermediates, which provide an efficient and facile method to prepare various organic compounds. Based on the type of CC bond formation in the cross-coupling reactions, the oxidative radical CC couplings are mainly divided into four types in this text: Coupling of Csp3H with CspH bonds; coupling of Csp3H with Csp2H bonds; coupling of Csp3H with Csp3H bonds; coupling of Csp2H with Csp2H bonds. This chapter describes the oxidative radical CC couplings, and discusses the mechanism study in oxidative radical coupling. Alkynylation of benzylic CH bonds that are not adjacent to a heteroatom is a possible route for the formation of Csp3Csp bonds. Oxidative radical CC couplings could be extended to synthesize more complex compounds, which are widely found in natural and pharmaceutical compounds. Styrenes and benzyl alcohols can react with unactivated arenes via cleavage of benzylic CC bonds to synthesize biaryls." @default.
- W4235697883 created "2022-05-12" @default.
- W4235697883 date "2016-08-26" @default.
- W4235697883 modified "2023-10-17" @default.
- W4235697883 title "Oxidative Radical Couplings" @default.
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- W4235697883 doi "https://doi.org/10.1002/9783527680986.ch5" @default.
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