Matches in SemOpenAlex for { <https://semopenalex.org/work/W4235700900> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W4235700900 endingPage "1704" @default.
- W4235700900 startingPage "1685" @default.
- W4235700900 abstract "This paper explores the use of simple summary statistics for analysing repeated measurements in randomized clinical trials with two treatments. Quite often the data for each patient may be effectively summarized by a pre-treatment mean and a post-treatment mean. Analysis of covariance is the method of choice and its superiority over analysis of post-treatment means or analysis of mean changes is quantified, as regards both reduced variance and avoidance of bias, using a simple model for the covariance structure between time points. Quantitative consideration is also given to practical issues in the design of repeated measures studies: the merits of having more than one pre-treatment measurement are demonstrated, and methods for determining sample sizes in repeated measures designs are provided. Several examples from clinical trials are presented, and broad practical recommendations are made. The examples support the value of the compound symmetry assumption as a realistic simplification in quantitative planning of repeated measures trials. The analysis using summary statistics makes no such assumption. However, allowance in design for alternative non-equal correlation structures can and should be made when necessary." @default.
- W4235700900 created "2022-05-12" @default.
- W4235700900 creator A5023436129 @default.
- W4235700900 creator A5036890206 @default.
- W4235700900 date "1992-01-01" @default.
- W4235700900 modified "2023-10-10" @default.
- W4235700900 title "Repeated measures in clinical trials: Analysis using mean summary statistics and its implications for design" @default.
- W4235700900 cites W1977833499 @default.
- W4235700900 cites W2019424823 @default.
- W4235700900 cites W2023174345 @default.
- W4235700900 cites W2028067695 @default.
- W4235700900 cites W2029615513 @default.
- W4235700900 cites W2045517754 @default.
- W4235700900 cites W2045526101 @default.
- W4235700900 cites W2050843646 @default.
- W4235700900 cites W2071381562 @default.
- W4235700900 cites W2092404711 @default.
- W4235700900 cites W2138839431 @default.
- W4235700900 cites W2316684546 @default.
- W4235700900 doi "https://doi.org/10.1002/sim.4780111304" @default.
- W4235700900 hasPublicationYear "1992" @default.
- W4235700900 type Work @default.
- W4235700900 citedByCount "454" @default.
- W4235700900 countsByYear W42357009002012 @default.
- W4235700900 countsByYear W42357009002013 @default.
- W4235700900 countsByYear W42357009002014 @default.
- W4235700900 countsByYear W42357009002015 @default.
- W4235700900 countsByYear W42357009002016 @default.
- W4235700900 countsByYear W42357009002017 @default.
- W4235700900 countsByYear W42357009002018 @default.
- W4235700900 countsByYear W42357009002019 @default.
- W4235700900 countsByYear W42357009002020 @default.
- W4235700900 countsByYear W42357009002021 @default.
- W4235700900 countsByYear W42357009002022 @default.
- W4235700900 countsByYear W42357009002023 @default.
- W4235700900 crossrefType "journal-article" @default.
- W4235700900 hasAuthorship W4235700900A5023436129 @default.
- W4235700900 hasAuthorship W4235700900A5036890206 @default.
- W4235700900 hasConcept C102959455 @default.
- W4235700900 hasConcept C105795698 @default.
- W4235700900 hasConcept C119340705 @default.
- W4235700900 hasConcept C121955636 @default.
- W4235700900 hasConcept C127413603 @default.
- W4235700900 hasConcept C129848803 @default.
- W4235700900 hasConcept C142724271 @default.
- W4235700900 hasConcept C144133560 @default.
- W4235700900 hasConcept C149782125 @default.
- W4235700900 hasConcept C178650346 @default.
- W4235700900 hasConcept C196083921 @default.
- W4235700900 hasConcept C2779268580 @default.
- W4235700900 hasConcept C2779318504 @default.
- W4235700900 hasConcept C33923547 @default.
- W4235700900 hasConcept C41008148 @default.
- W4235700900 hasConcept C535046627 @default.
- W4235700900 hasConcept C71924100 @default.
- W4235700900 hasConcept C78519656 @default.
- W4235700900 hasConceptScore W4235700900C102959455 @default.
- W4235700900 hasConceptScore W4235700900C105795698 @default.
- W4235700900 hasConceptScore W4235700900C119340705 @default.
- W4235700900 hasConceptScore W4235700900C121955636 @default.
- W4235700900 hasConceptScore W4235700900C127413603 @default.
- W4235700900 hasConceptScore W4235700900C129848803 @default.
- W4235700900 hasConceptScore W4235700900C142724271 @default.
- W4235700900 hasConceptScore W4235700900C144133560 @default.
- W4235700900 hasConceptScore W4235700900C149782125 @default.
- W4235700900 hasConceptScore W4235700900C178650346 @default.
- W4235700900 hasConceptScore W4235700900C196083921 @default.
- W4235700900 hasConceptScore W4235700900C2779268580 @default.
- W4235700900 hasConceptScore W4235700900C2779318504 @default.
- W4235700900 hasConceptScore W4235700900C33923547 @default.
- W4235700900 hasConceptScore W4235700900C41008148 @default.
- W4235700900 hasConceptScore W4235700900C535046627 @default.
- W4235700900 hasConceptScore W4235700900C71924100 @default.
- W4235700900 hasConceptScore W4235700900C78519656 @default.
- W4235700900 hasIssue "13" @default.
- W4235700900 hasLocation W42357009001 @default.
- W4235700900 hasOpenAccess W4235700900 @default.
- W4235700900 hasPrimaryLocation W42357009001 @default.
- W4235700900 hasRelatedWork W1645064579 @default.
- W4235700900 hasRelatedWork W2012610170 @default.
- W4235700900 hasRelatedWork W2034726400 @default.
- W4235700900 hasRelatedWork W2037678252 @default.
- W4235700900 hasRelatedWork W2103417018 @default.
- W4235700900 hasRelatedWork W2117333491 @default.
- W4235700900 hasRelatedWork W2168660592 @default.
- W4235700900 hasRelatedWork W2325137977 @default.
- W4235700900 hasRelatedWork W2408977128 @default.
- W4235700900 hasRelatedWork W4235700900 @default.
- W4235700900 hasVolume "11" @default.
- W4235700900 isParatext "false" @default.
- W4235700900 isRetracted "false" @default.
- W4235700900 workType "article" @default.