Matches in SemOpenAlex for { <https://semopenalex.org/work/W4235950800> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4235950800 endingPage "24" @default.
- W4235950800 startingPage "21" @default.
- W4235950800 abstract ": Background: Treatment of infectious diseases is becoming more challenging with each passing year. This is especially true for infections caused by Pseudomonas aeruginosa, an opportunistic pathogen with the ability to rapidly develop resistance to multiple classes of antibiotics. Objectives: This study was conducted to determine the prevalence of metallo-β-lactamase (MBL)âproducing strains among multidrug-resistant P. aeruginosa strains isolated from burn patients. Materials and Methods: The isolates were identified, tested for susceptibility to various antimicrobial agents, and screened for the presence of MβLs by using the double-disk synergy test. The minimal inhibitory concentration of imipenem was determined by microplate broth dilution method on Mueller-Hinton agar. To detect VIM, SIM, and GIM MBLs, the isolates were subjected to polymerase chain reaction. Results: In this study, we identified 100 P. aeruginosa isolates from 176 clinical specimens obtained from burn patients. The isolates showed maximum resistance to ampicillin (100%), ceftazidime (94%), and ceftriaxone (89%). The CLSI-MBL phenotypic test showed that of the 100 P. aeruginosa isolates, 22 (22%) were positive for MBL production in the double-disk synergy test. Of the 22 MBL-positive P. aeruginosa isolates, 8 were resistant to imipenem. PCR analysis showed that 8 isolates were positive for blaVIM1. The other genes blaSIM1 and blaGIM1 were not detected. Conclusions: The study results demonstrate the serious therapeutic threat of the spread of MBL producers among P. aeruginosa populations. Metallo-β-lactamases were detected in 22% of imipenem-resistant P. aeruginosa isolates. Early detection and infection-control practices are the best antimicrobial strategies for this organism; therefore, systematic surveillance to detect MBL producers is necessary." @default.
- W4235950800 created "2022-05-12" @default.
- W4235950800 creator A5011239558 @default.
- W4235950800 creator A5016671464 @default.
- W4235950800 creator A5020529146 @default.
- W4235950800 creator A5048466363 @default.
- W4235950800 creator A5067998607 @default.
- W4235950800 creator A5070312964 @default.
- W4235950800 date "2012-12-26" @default.
- W4235950800 modified "2023-09-26" @default.
- W4235950800 title "First Survey of Metallo-β–Lactamase Producers in Clinical Isolates of Pseudomonas aeruginosa From a Referral Burn Center in Kurdistan Province" @default.
- W4235950800 cites W1971964352 @default.
- W4235950800 cites W1989336544 @default.
- W4235950800 cites W2015616353 @default.
- W4235950800 cites W2034129786 @default.
- W4235950800 cites W2074042278 @default.
- W4235950800 cites W2074709034 @default.
- W4235950800 cites W2097522236 @default.
- W4235950800 cites W2098206739 @default.
- W4235950800 cites W2098232570 @default.
- W4235950800 cites W2099257288 @default.
- W4235950800 cites W2122273366 @default.
- W4235950800 cites W2124827139 @default.
- W4235950800 cites W2131185071 @default.
- W4235950800 cites W2135845345 @default.
- W4235950800 cites W2137333677 @default.
- W4235950800 cites W2172289831 @default.
- W4235950800 doi "https://doi.org/10.5812/jjnpp.3546" @default.
- W4235950800 hasPublicationYear "2012" @default.
- W4235950800 type Work @default.
- W4235950800 citedByCount "0" @default.
- W4235950800 crossrefType "journal-article" @default.
- W4235950800 hasAuthorship W4235950800A5011239558 @default.
- W4235950800 hasAuthorship W4235950800A5016671464 @default.
- W4235950800 hasAuthorship W4235950800A5020529146 @default.
- W4235950800 hasAuthorship W4235950800A5048466363 @default.
- W4235950800 hasAuthorship W4235950800A5067998607 @default.
- W4235950800 hasAuthorship W4235950800A5070312964 @default.
- W4235950800 hasBestOaLocation W42359508001 @default.
- W4235950800 hasConcept C133936738 @default.
- W4235950800 hasConcept C176947019 @default.
- W4235950800 hasConcept C2776021129 @default.
- W4235950800 hasConcept C2776968632 @default.
- W4235950800 hasConcept C2777427914 @default.
- W4235950800 hasConcept C2777637488 @default.
- W4235950800 hasConcept C2779631663 @default.
- W4235950800 hasConcept C2780493024 @default.
- W4235950800 hasConcept C2909292399 @default.
- W4235950800 hasConcept C4937899 @default.
- W4235950800 hasConcept C501593827 @default.
- W4235950800 hasConcept C523546767 @default.
- W4235950800 hasConcept C54355233 @default.
- W4235950800 hasConcept C71924100 @default.
- W4235950800 hasConcept C86803240 @default.
- W4235950800 hasConcept C89423630 @default.
- W4235950800 hasConcept C94665300 @default.
- W4235950800 hasConceptScore W4235950800C133936738 @default.
- W4235950800 hasConceptScore W4235950800C176947019 @default.
- W4235950800 hasConceptScore W4235950800C2776021129 @default.
- W4235950800 hasConceptScore W4235950800C2776968632 @default.
- W4235950800 hasConceptScore W4235950800C2777427914 @default.
- W4235950800 hasConceptScore W4235950800C2777637488 @default.
- W4235950800 hasConceptScore W4235950800C2779631663 @default.
- W4235950800 hasConceptScore W4235950800C2780493024 @default.
- W4235950800 hasConceptScore W4235950800C2909292399 @default.
- W4235950800 hasConceptScore W4235950800C4937899 @default.
- W4235950800 hasConceptScore W4235950800C501593827 @default.
- W4235950800 hasConceptScore W4235950800C523546767 @default.
- W4235950800 hasConceptScore W4235950800C54355233 @default.
- W4235950800 hasConceptScore W4235950800C71924100 @default.
- W4235950800 hasConceptScore W4235950800C86803240 @default.
- W4235950800 hasConceptScore W4235950800C89423630 @default.
- W4235950800 hasConceptScore W4235950800C94665300 @default.
- W4235950800 hasIssue "1" @default.
- W4235950800 hasLocation W42359508001 @default.
- W4235950800 hasOpenAccess W4235950800 @default.
- W4235950800 hasPrimaryLocation W42359508001 @default.
- W4235950800 hasRelatedWork W2154199801 @default.
- W4235950800 hasRelatedWork W2201789966 @default.
- W4235950800 hasRelatedWork W2356311837 @default.
- W4235950800 hasRelatedWork W2385999912 @default.
- W4235950800 hasRelatedWork W2399842400 @default.
- W4235950800 hasRelatedWork W2888673045 @default.
- W4235950800 hasRelatedWork W4235504288 @default.
- W4235950800 hasRelatedWork W4235950800 @default.
- W4235950800 hasRelatedWork W811677459 @default.
- W4235950800 hasRelatedWork W2739649700 @default.
- W4235950800 hasVolume "7" @default.
- W4235950800 isParatext "false" @default.
- W4235950800 isRetracted "false" @default.
- W4235950800 workType "article" @default.