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- W4236021580 abstract "Objectives: Pancreatic groove carcinoma usually presents with duodenal stenosis. This report describes the clinicopathologic features of five cases. Methods: All the clinical and radiologic features were reviewed retrospectively and analyzed to identify correlations with the histological findings. Results: Vomiting was an initial symptom in all cases, but obstructive jaundice was not inevitable until the disease progress. Hypotonic duodenography demonstrated severe postbulbar stenosis. Pathologic findings of biopsy specimens showed no evidence of malignancy at the early stage. Computed Tomography revealed a hypovascular mass. Magnetic resonance imaging indicated a hypointense mass on T1-weighted, and an iso- to slightly hyperintense mass on T2 images. Macroscopically, the stenosis appeared to be the result of a hard, yellowish-white tumor invading the duodenal wall. Histopathologically, an adenocarcinoma arising from the groove infiltrated the submucosal layer of the duodenum circumferentially. No cancer cells were found in the mucosa at the early stage. The intrapancreatic common bile duct was involved at the advanced stage. Conclusions: We believe that these features resulted from the anatomic characteristics of the groove involvement and that the string-stricture of the duodenum resulted from invasion of the groove tumor into the submucosal layer around the wall." @default.
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- W4236021580 date "2006-11-01" @default.
- W4236021580 modified "2023-09-26" @default.
- W4236021580 title "CLINICOPATHOLOGIC STUDY ON PANCREATIC GROOVE CARCINOMA" @default.
- W4236021580 doi "https://doi.org/10.1097/00006676-200611000-00226" @default.
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