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- W4236034829 abstract "Most investigations of pulmonary embolism (PE), deep venous thrombosis (DVT), and venous thromboembolism (VTE) in countries in Asia suggest that the rate of diagnosis is lower in Asians than in persons from North America or Europe. Age-adjusted rates of diagnosis of PE were lower in Asians/Pacific Islanders than in African Americans and whites. The lower mortality among Asians/Pacific Islanders was independent of the lower rate of all-cause hospitalizations. Differences in coagulation factors may contribute to the low rate of VTE in Asians. Asians appear to be more sensitive to warfarin than whites. Clinical problems with toxicity and dosage adjustment of warfarin have been found in patients with a genetic polymorphism to CYP2C9, but this polymorphism does not appear to be more frequent in Asians than whites. Differences in the activity of CYP2C9 between Asians and whites may relate to differences in the pharmacokenetics of warfarin." @default.
- W4236034829 created "2022-05-12" @default.
- W4236034829 date "2016-04-08" @default.
- W4236034829 modified "2023-10-17" @default.
- W4236034829 title "Pulmonary thromboembolism in Asians/Pacific Islanders" @default.
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- W4236034829 doi "https://doi.org/10.1002/9781119039112.ch16" @default.
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