Matches in SemOpenAlex for { <https://semopenalex.org/work/W4236039632> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4236039632 abstract "<b>Objectives:</b> In African-born blacks living in America, we determined by BMI category: (a) prevalence of Abnl-GT; (b) diagnostic value and reproducibility of HbA<sub>1c</sub>, fructosamine and GA. <p><b>Methods</b>: Participants (n=416, male: 66%; BMI: 27.7±4.5kg/m<sup>2</sup> (mean±SD)) had OGTT with HbA<sub>1c</sub>, GA, and fructosamine assayed. These glycemic markers were repeated 11±7d later. Abnl-GT diagnosis required: 0h≥5.6mmol/L (≥100 mg/dL) and/or 2h≥7.8mmol/L (≥140 mg/dL). Thresholds for HbA<sub>1c</sub>, GA and fructosamine were the values at the 75<sup>th</sup> percentile for the population (39 mmol/mol (5.7%), 14.2%, 234µmol/L, respectively). </p> <p><b>Results</b>: Abnl-GT prevalence in the nonobese and obese were: 34% vs. 42%, (<i>P</i>=0.124). Reproducibility was excellent for HbA<sub>1c</sub> and GA (both κ≥0.8), but moderate for fructosamine (κ=0.6). Focusing on HbA<sub>1c</sub> and GA in the nonobese, we found as single tests the sensitivities of HbA<sub>1c</sub> and GA were: 36% vs. 37%, (<i>P</i>=0.529). Combining HbA<sub>1c </sub>and GA, sensitivity increased to 58% because GA identified 37% of Africans with Abnl-GT not detected by HbA<sub>1c</sub> (<i>P</i>-value: both tests vs. HbA<sub>1c</sub> alone <0.001). For the obese, sensitivities for HbA<sub>1c</sub>, GA and the combined tests were: 60%, 27%, 67%, respectively. Combined test sensitivity did not differ from HbA<sub>1c</sub> alone (<i>P</i>=0.25) because GA detected only 10% of obese Africans with Abnl-GT not detected by HbA<sub>1c</sub>. </p> <p><b>Conclusion</b>: Adding GA to HbA<sub>1c</sub> improves detection of Abnl-GT in nonobese Africans.</p> <br><b></b>" @default.
- W4236039632 created "2022-05-12" @default.
- W4236039632 creator A5005673337 @default.
- W4236039632 creator A5011607008 @default.
- W4236039632 creator A5013857769 @default.
- W4236039632 creator A5014776394 @default.
- W4236039632 creator A5015223159 @default.
- W4236039632 creator A5021181045 @default.
- W4236039632 creator A5028526421 @default.
- W4236039632 creator A5034381602 @default.
- W4236039632 creator A5071420054 @default.
- W4236039632 creator A5089010090 @default.
- W4236039632 creator A5090900196 @default.
- W4236039632 date "2020-08-17" @default.
- W4236039632 modified "2023-10-16" @default.
- W4236039632 title "Improved Detection of Abnormal Glucose Tolerance in Africans: The Value of Combining Hemoglobin A1c with Glycated Albumin" @default.
- W4236039632 doi "https://doi.org/10.2337/figshare.12690023.v1" @default.
- W4236039632 hasPublicationYear "2020" @default.
- W4236039632 type Work @default.
- W4236039632 citedByCount "0" @default.
- W4236039632 crossrefType "posted-content" @default.
- W4236039632 hasAuthorship W4236039632A5005673337 @default.
- W4236039632 hasAuthorship W4236039632A5011607008 @default.
- W4236039632 hasAuthorship W4236039632A5013857769 @default.
- W4236039632 hasAuthorship W4236039632A5014776394 @default.
- W4236039632 hasAuthorship W4236039632A5015223159 @default.
- W4236039632 hasAuthorship W4236039632A5021181045 @default.
- W4236039632 hasAuthorship W4236039632A5028526421 @default.
- W4236039632 hasAuthorship W4236039632A5034381602 @default.
- W4236039632 hasAuthorship W4236039632A5071420054 @default.
- W4236039632 hasAuthorship W4236039632A5089010090 @default.
- W4236039632 hasAuthorship W4236039632A5090900196 @default.
- W4236039632 hasBestOaLocation W42360396321 @default.
- W4236039632 hasConcept C105795698 @default.
- W4236039632 hasConcept C122048520 @default.
- W4236039632 hasConcept C126322002 @default.
- W4236039632 hasConcept C134018914 @default.
- W4236039632 hasConcept C2779306644 @default.
- W4236039632 hasConcept C2781357877 @default.
- W4236039632 hasConcept C2908647359 @default.
- W4236039632 hasConcept C33923547 @default.
- W4236039632 hasConcept C71924100 @default.
- W4236039632 hasConcept C99454951 @default.
- W4236039632 hasConceptScore W4236039632C105795698 @default.
- W4236039632 hasConceptScore W4236039632C122048520 @default.
- W4236039632 hasConceptScore W4236039632C126322002 @default.
- W4236039632 hasConceptScore W4236039632C134018914 @default.
- W4236039632 hasConceptScore W4236039632C2779306644 @default.
- W4236039632 hasConceptScore W4236039632C2781357877 @default.
- W4236039632 hasConceptScore W4236039632C2908647359 @default.
- W4236039632 hasConceptScore W4236039632C33923547 @default.
- W4236039632 hasConceptScore W4236039632C71924100 @default.
- W4236039632 hasConceptScore W4236039632C99454951 @default.
- W4236039632 hasLocation W42360396321 @default.
- W4236039632 hasLocation W42360396322 @default.
- W4236039632 hasLocation W42360396323 @default.
- W4236039632 hasOpenAccess W4236039632 @default.
- W4236039632 hasPrimaryLocation W42360396321 @default.
- W4236039632 hasRelatedWork W1966504330 @default.
- W4236039632 hasRelatedWork W1974041167 @default.
- W4236039632 hasRelatedWork W1976451610 @default.
- W4236039632 hasRelatedWork W1979139803 @default.
- W4236039632 hasRelatedWork W2012578977 @default.
- W4236039632 hasRelatedWork W2037631372 @default.
- W4236039632 hasRelatedWork W2040058909 @default.
- W4236039632 hasRelatedWork W2153907787 @default.
- W4236039632 hasRelatedWork W2748952813 @default.
- W4236039632 hasRelatedWork W70725711 @default.
- W4236039632 isParatext "false" @default.
- W4236039632 isRetracted "false" @default.
- W4236039632 workType "article" @default.