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- W4236048900 abstract "This study was investigated the effects of exercise on ACh, AChE, β-amyloid, apolipoprotein expression and cognitive functions in scopolamine-induced memory impairment rats. At 7 weeks of age, SD rats (N=40) were induced memory impairment by administering scopolamine. A scopolamine-induced rats were randomly assigned to a control (CON, n=10), scopolamine-control(SCO-CON, n=10), low-intensity exercise (SCO-LEX, n=10), high-intensity exercise (SCO-HEX, n=10). The rats were trained progressively on a treadmill, five days per weeks for eight weeks following treadmill running programs: low-intensity (1-4 weeks: 10 m/min for 30 mins, 5-8 weeks: 12m/min for 30mins) and high-intensity (1-4 weeks: 15 m/min for 30 mins, 5-8 weeks: 16m/min for 30 mins). Both exercise groups significantly reduced β-amyloid and ApoE protein levels. ACh levels were significantly increased in both exercise groups. Both exercise groups showed a significant decrease of escape latency compared with the control group. In conclusion, treadmill exercise for 8 weeks was effective method to improve cognitive function, regardless of exercise intensity." @default.
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- W4236048900 date "2016-06-30" @default.
- W4236048900 modified "2023-10-16" @default.
- W4236048900 title "Effects of Treadmill Exercise on ACh, AChE, β-amyloid, Apolipoprotein Expression and Cognitive Function in Brain of Memory Impairment Rat" @default.
- W4236048900 doi "https://doi.org/10.21086/ksles.2016.06.23.3.422" @default.
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