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- W4236055871 abstract "The management of hypertension in renal disease is best understood by classifying patients according to the stage of their chronic kidney disease (CKD). Many of the pathophysiological mechanisms are common to all patients, but in post-transplant recipients there are additional factors to be considered. The benefits of good blood pressure control in CKD are a slowing in the rate of progression of renal disease and a reduction in cardiovascular morbidity and all-cause mortality. In CKD stage 5, the aim is solely to reduce cardiovascular morbidity and mortality; the evidence of benefit here is more controversial, with several studies showing worse outcomes in patients with low blood pressure. In renal transplant recipients, good blood pressure control is advantageous for the long-term outcome of graft survival, in addition to reducing cardiovascular morbidity and mortality. Renal transplant recipients are generally treated according to the guidelines for CKD. However, consideration of the dosing of corticosteroids and choice of calcineurin inhibitors can play an important role in reducing the incidence of hypertension." @default.
- W4236055871 created "2022-05-12" @default.
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- W4236055871 date "2019-08-01" @default.
- W4236055871 modified "2023-09-30" @default.
- W4236055871 title "Management of hypertension in renal disease" @default.
- W4236055871 doi "https://doi.org/10.1016/j.mpmed.2019.05.006" @default.
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