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- W4236063398 abstract "Increasing numbers of international, national and state/provincial health organizations in the developed and developing world recommend postexposure prophylaxis (PEP) following potential sexual exposure to HIV. The evidence for these policies is extrapolated from occupational healthcare worker, perinatal prophylaxis and animal studies. There is no direct evidence of PEP efficacy after sexual exposures. Studies addressing potential increases in risk behavior, toxicities and cost–effectiveness are encouraging. Considerations for offering PEP include the timing and characteristics of the exposure and the HIV status of the source and exposed individuals. PEP includes 28 days of a combination antiretroviral drug regimen containing two or more drugs and associated laboratory testing, counseling and referrals. PEP service delivery challenges include ensuring adequate access to services, optimizing PEP adherence and facilitating follow-up HIV testing and counseling. Men who have sex with men, sexual assault survivors, children and adolescents, and individuals in resource-limited settings present unique needs and challenges." @default.
- W4236063398 created "2022-05-12" @default.
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- W4236063398 date "2007-05-01" @default.
- W4236063398 modified "2023-10-14" @default.
- W4236063398 title "Postexposure prophylaxis after sexual exposure to HIV" @default.
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- W4236063398 doi "https://doi.org/10.2217/17469600.1.1.35" @default.
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