Matches in SemOpenAlex for { <https://semopenalex.org/work/W4236064119> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W4236064119 endingPage "390" @default.
- W4236064119 startingPage "390" @default.
- W4236064119 abstract ".Sera from subjects vaccinated with the Pasteur Merieux (PM) inactivated hepatitis A vaccine (AVAXIMTM) have been analysed in order: (1) to assess comparability of the results provided by a modied radio-immunoassay (mRIA) in the different laboratories involved in testings of sera during clinical trials and by enzyme-linked immunoabsorbent assay (ELISA) used during development of other inactivated hepatitis A vaccines; (2) to describe the IgM responses elicited by this vaccine compared with one control vaccine [HAVRIXTM, 720 ELISA antigens units; Smithkline Beecham (SB), Rixensart, Belgium]; (3) to provide comparative data between the PM vaccine and the SB vaccine on neutralizing activities of vaccine-induced antibodies. Vaccine-induced antibody titres evaluated by a mRIA in different laboratories correlated well and validated the comparability of the results obtained in various vaccine trials conducted by PM. Geometric mean titres (GMTs) expressed as milli-international units (mIU/ml) were higher with ELISA especially after the rst dose, but seroconversion rates were similar and a good correlation was found between the two assays. IgM vaccine-induced antibodies were detectable in nearly all vaccinated subjects from week 2 after vaccination, with a peak titre between weeks 2 and 4 after the rst dose. Comparison of GMTs by the Student Fisher t-test was statistically signicant (P < 0.05) only at week 2 with higher titres in PM vaccinees. Neutralizing antibodies were detected after vaccination with the PM inactivated hepatitis A vaccine. The titres gradually increased between the second week after the rst dose and the booster dose (week 24). A strong booster effect of the second dose on neutralizing titres was observed. Seroneutralizing titres induced at week 2 in subjects vaccinated with the PM inactivated hepatitis A vaccine were statistically signicantly higher (P < 0.05) from those induced by the SB vaccine." @default.
- W4236064119 created "2022-05-12" @default.
- W4236064119 creator A5068041767 @default.
- W4236064119 creator A5081470680 @default.
- W4236064119 date "2006-12-01" @default.
- W4236064119 modified "2023-10-16" @default.
- W4236064119 doi "https://doi.org/10.1016/s1479-666x(06)80127-7" @default.
- W4236064119 hasPublicationYear "2006" @default.
- W4236064119 type Work @default.
- W4236064119 citedByCount "0" @default.
- W4236064119 crossrefType "journal-article" @default.
- W4236064119 hasAuthorship W4236064119A5068041767 @default.
- W4236064119 hasAuthorship W4236064119A5081470680 @default.
- W4236064119 hasConcept C12590561 @default.
- W4236064119 hasConcept C159047783 @default.
- W4236064119 hasConcept C159654299 @default.
- W4236064119 hasConcept C203014093 @default.
- W4236064119 hasConcept C22070199 @default.
- W4236064119 hasConcept C2776872762 @default.
- W4236064119 hasConcept C2777451964 @default.
- W4236064119 hasConcept C2780420688 @default.
- W4236064119 hasConcept C2780799908 @default.
- W4236064119 hasConcept C2780801004 @default.
- W4236064119 hasConcept C32611913 @default.
- W4236064119 hasConcept C71924100 @default.
- W4236064119 hasConceptScore W4236064119C12590561 @default.
- W4236064119 hasConceptScore W4236064119C159047783 @default.
- W4236064119 hasConceptScore W4236064119C159654299 @default.
- W4236064119 hasConceptScore W4236064119C203014093 @default.
- W4236064119 hasConceptScore W4236064119C22070199 @default.
- W4236064119 hasConceptScore W4236064119C2776872762 @default.
- W4236064119 hasConceptScore W4236064119C2777451964 @default.
- W4236064119 hasConceptScore W4236064119C2780420688 @default.
- W4236064119 hasConceptScore W4236064119C2780799908 @default.
- W4236064119 hasConceptScore W4236064119C2780801004 @default.
- W4236064119 hasConceptScore W4236064119C32611913 @default.
- W4236064119 hasConceptScore W4236064119C71924100 @default.
- W4236064119 hasIssue "6" @default.
- W4236064119 hasLocation W42360641191 @default.
- W4236064119 hasOpenAccess W4236064119 @default.
- W4236064119 hasPrimaryLocation W42360641191 @default.
- W4236064119 hasRelatedWork W1919491466 @default.
- W4236064119 hasRelatedWork W1971240455 @default.
- W4236064119 hasRelatedWork W2114584134 @default.
- W4236064119 hasRelatedWork W2354916412 @default.
- W4236064119 hasRelatedWork W2365408462 @default.
- W4236064119 hasRelatedWork W2377517152 @default.
- W4236064119 hasRelatedWork W2392775640 @default.
- W4236064119 hasRelatedWork W2395989777 @default.
- W4236064119 hasRelatedWork W2399446619 @default.
- W4236064119 hasRelatedWork W4283719395 @default.
- W4236064119 hasVolume "4" @default.
- W4236064119 isParatext "false" @default.
- W4236064119 isRetracted "false" @default.
- W4236064119 workType "article" @default.