FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4236077907> ?p ?o ?g. }

• W4236077907 abstract "Abstract Background Nitric oxide is a small gaseous molecule with significant bioactivity. It has been observed that NO may have a dual role dependent on its production and concentrations in the bone microenvironment. The objective of the study was to assess the concentration of total nitric oxide malonyldialdehyde, nitrotyrosine, and asymmetric dimethylarginine in the serum of patients with mandibular fractures and to understand the relationship between these compounds, in order to expand the knowledge base of the role of nitric oxide and its activity indicators in the process of bone fracture healing.Material and methods The study included patients with mandibular fractures who were undergoing inpatient and outpatient treatments. Results were analyzed with respect to the measurement time. Total nitric oxide concentration in the blood serum was determined according to the Griess reaction, while the concentration of malonyldialdehyde, nitrotyrosine, and asymmetric dimethylarginine was estimated using the immunoenzymatic method (i.e. enzyme-linked immunosorbent assay).Results Before procedure as well as on the first day and 2 and 6 weeks after the procedure, higher concentrations of total nitric oxide and lower concentrations of malonyldialdehyde were observed in the blood serum of patients with mandibular fractures compared to the control group. No statistically significant differences were found in nitrotyrosine concentrations in the blood serum of patients throughout the measurement period. However, a significantly higher asymmetric dimethylarginine concentration was observed in the patient serum before the procedure and on the first day of operation as compared with the control group. Analysis of the results observed in patient serum with respect to the number of fractures within the mandible demonstrated the same trend of concentrations for the tested compounds for the entire study group.Conclusions In summary, our results revealed that the intensity of local processes resulting from mandibular fractures is associated with the concentration of nitric oxide, confirming its significant role, as well as that of its indicators, in the process of bone fracture healing in this patient population." @default.
• W4236077907 created "2022-05-12" @default.
• W4236077907 creator A5034832036 @default.
• W4236077907 creator A5041439313 @default.
• W4236077907 creator A5050528980 @default.
• W4236077907 creator A5055272591 @default.
• W4236077907 creator A5056412582 @default.
• W4236077907 creator A5062932374 @default.
• W4236077907 creator A5081549831 @default.
• W4236077907 date "2020-01-23" @default.
• W4236077907 modified "2023-09-26" @default.
• W4236077907 title "Levels of Biological Markers of Nitric Oxide in Serum of Patients with Mandible Factures" @default.
• W4236077907 doi "https://doi.org/10.21203/rs.2.21730/v1" @default.
• W4236077907 hasPublicationYear "2020" @default.
• W4236077907 type Work @default.
• W4236077907 citedByCount "0" @default.
• W4236077907 crossrefType "posted-content" @default.
• W4236077907 hasAuthorship W4236077907A5034832036 @default.
• W4236077907 hasAuthorship W4236077907A5041439313 @default.
• W4236077907 hasAuthorship W4236077907A5050528980 @default.
• W4236077907 hasAuthorship W4236077907A5055272591 @default.
• W4236077907 hasAuthorship W4236077907A5056412582 @default.
• W4236077907 hasAuthorship W4236077907A5062932374 @default.
• W4236077907 hasAuthorship W4236077907A5081549831 @default.
• W4236077907 hasBestOaLocation W42360779071 @default.
• W4236077907 hasConcept C126322002 @default.
• W4236077907 hasConcept C134018914 @default.
• W4236077907 hasConcept C185592680 @default.
• W4236077907 hasConcept C2777468819 @default.
• W4236077907 hasConcept C2777622882 @default.
• W4236077907 hasConcept C2779385521 @default.
• W4236077907 hasConcept C2779877776 @default.
• W4236077907 hasConcept C515207424 @default.
• W4236077907 hasConcept C519581460 @default.
• W4236077907 hasConcept C55493867 @default.
• W4236077907 hasConcept C71924100 @default.
• W4236077907 hasConceptScore W4236077907C126322002 @default.
• W4236077907 hasConceptScore W4236077907C134018914 @default.
• W4236077907 hasConceptScore W4236077907C185592680 @default.
• W4236077907 hasConceptScore W4236077907C2777468819 @default.
• W4236077907 hasConceptScore W4236077907C2777622882 @default.
• W4236077907 hasConceptScore W4236077907C2779385521 @default.
• W4236077907 hasConceptScore W4236077907C2779877776 @default.
• W4236077907 hasConceptScore W4236077907C515207424 @default.
• W4236077907 hasConceptScore W4236077907C519581460 @default.
• W4236077907 hasConceptScore W4236077907C55493867 @default.
• W4236077907 hasConceptScore W4236077907C71924100 @default.
• W4236077907 hasLocation W42360779071 @default.
• W4236077907 hasOpenAccess W4236077907 @default.
• W4236077907 hasPrimaryLocation W42360779071 @default.
• W4236077907 hasRelatedWork W11152159 @default.
• W4236077907 hasRelatedWork W2177219 @default.
• W4236077907 hasRelatedWork W4988946 @default.
• W4236077907 hasRelatedWork W5046846 @default.
• W4236077907 hasRelatedWork W7690208 @default.
• W4236077907 hasRelatedWork W807710 @default.
• W4236077907 hasRelatedWork W8250741 @default.
• W4236077907 hasRelatedWork W8857743 @default.
• W4236077907 hasRelatedWork W9340346 @default.
• W4236077907 hasRelatedWork W4502897 @default.
• W4236077907 isParatext "false" @default.
• W4236077907 isRetracted "false" @default.
• W4236077907 workType "article" @default.