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- W4236079275 abstract "A known interferon stimulator, polyriboinosinic acid:polyribocytidylic acid (rI:rC), was shown to have a protective effect against a highly tumorigenic variant of the murine sarcoma virus (Moloney) designated as (MSV-PV). Mice treated intraperitoneally with different regimens of rI:rC survived significantly longer than untreated controls. The treatment was effective whether the infection with MSV-PV was intraperitoneal or intracerebral. The antiviral effectiveness of rI:rC was demonstrated by marked reduction of viral replication. The kinetic study of interferon induction by rI:rC showed a peak titer of interferon occurring at 18 hr after injection, followed by a rapid decrease in titer by 24 hr." @default.
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- W4236079275 date "1969-01-01" @default.
- W4236079275 modified "2023-10-16" @default.
- W4236079275 title "Effectiveness of Therapy with a Multistranded Synthetic Polynucleotide Complex Against a Murine Sarcoma Virus" @default.
- W4236079275 doi "https://doi.org/10.1128/aem.18.3.474-478.1969" @default.
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