Matches in SemOpenAlex for { <https://semopenalex.org/work/W4236274738> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4236274738 abstract "Abstract Background The goal of this study was to compare the clinical results of conventional transcatheter arterial chemoembolization (C-TACE) and doxorubicin-eluting bead transcatheter arterial chemoembolization (D-TACE) combined with endovascular stent implantation with an iodine-125 seed strand in hepatocellular carcinoma (HCC) patients with main portal vein tumor thrombus (MPVTT). Methods This study was a prospective controlled study with follow-up dates spanning from Mar 2015 to Feb 2020. Patients with both HCC and MPVTT were randomly divided into two groups. Portal vein stents with iodine-125 seed strands were implanted first; then, C-TACE or D-TACE was administered to all patients. Objective response rates were assessed. The time to disease progression and survival rate were compared between the two groups. Results A total of 26 patients were enrolled, with 13 in each group. During follow-up, the portal stent patency times were 112.3±98.2 days in the C-TACE group and 101.7±90.4 days in the D-TACE group. The time to disease progression was 42 days in the C-TACE group and 120 days in the D-TACE group (p=0.03). The overall survival time from the first intervention procedure was 216 days in the C-TACE group and 239 days in the D-TACE group (p=0.047). The D-TACE group was superior to the C-TACE group in terms of progression-free survival (PFS) and overall survival (OS) times. Conclusion Endovascular implantation of a stent with an iodine-125 seed strand combined with TACE is safe and effective in HCC patients with MPVTT. Compared to C-TACE, D-TACE achieves more benefits regarding PFS and OS. Trial registration This study was a cohort study, no health-related interventions to evaluate the effects on health outcomes. This study wasn’t a clinical trial." @default.
- W4236274738 created "2022-05-12" @default.
- W4236274738 creator A5015358679 @default.
- W4236274738 creator A5017702755 @default.
- W4236274738 creator A5021384291 @default.
- W4236274738 creator A5034016735 @default.
- W4236274738 creator A5050768970 @default.
- W4236274738 creator A5066054702 @default.
- W4236274738 creator A5067169051 @default.
- W4236274738 creator A5071375088 @default.
- W4236274738 creator A5077322975 @default.
- W4236274738 creator A5084369837 @default.
- W4236274738 date "2020-09-28" @default.
- W4236274738 modified "2023-09-26" @default.
- W4236274738 title "Evaluation of doxorubicin-eluting bead transcatheter arterial chemoembolization combined with endovascular brachytherapy for hepatocellular carcinoma with main portal vein tumor thrombus" @default.
- W4236274738 doi "https://doi.org/10.21203/rs.3.rs-52846/v2" @default.
- W4236274738 hasPublicationYear "2020" @default.
- W4236274738 type Work @default.
- W4236274738 citedByCount "0" @default.
- W4236274738 crossrefType "posted-content" @default.
- W4236274738 hasAuthorship W4236274738A5015358679 @default.
- W4236274738 hasAuthorship W4236274738A5017702755 @default.
- W4236274738 hasAuthorship W4236274738A5021384291 @default.
- W4236274738 hasAuthorship W4236274738A5034016735 @default.
- W4236274738 hasAuthorship W4236274738A5050768970 @default.
- W4236274738 hasAuthorship W4236274738A5066054702 @default.
- W4236274738 hasAuthorship W4236274738A5067169051 @default.
- W4236274738 hasAuthorship W4236274738A5071375088 @default.
- W4236274738 hasAuthorship W4236274738A5077322975 @default.
- W4236274738 hasAuthorship W4236274738A5084369837 @default.
- W4236274738 hasBestOaLocation W42362747381 @default.
- W4236274738 hasConcept C126322002 @default.
- W4236274738 hasConcept C126838900 @default.
- W4236274738 hasConcept C141071460 @default.
- W4236274738 hasConcept C2776231280 @default.
- W4236274738 hasConcept C2776694085 @default.
- W4236274738 hasConcept C2777416452 @default.
- W4236274738 hasConcept C2778019345 @default.
- W4236274738 hasConcept C2778455285 @default.
- W4236274738 hasConcept C2778583881 @default.
- W4236274738 hasConcept C2779033008 @default.
- W4236274738 hasConcept C2781303535 @default.
- W4236274738 hasConcept C2781362458 @default.
- W4236274738 hasConcept C509974204 @default.
- W4236274738 hasConcept C71924100 @default.
- W4236274738 hasConcept C90924648 @default.
- W4236274738 hasConceptScore W4236274738C126322002 @default.
- W4236274738 hasConceptScore W4236274738C126838900 @default.
- W4236274738 hasConceptScore W4236274738C141071460 @default.
- W4236274738 hasConceptScore W4236274738C2776231280 @default.
- W4236274738 hasConceptScore W4236274738C2776694085 @default.
- W4236274738 hasConceptScore W4236274738C2777416452 @default.
- W4236274738 hasConceptScore W4236274738C2778019345 @default.
- W4236274738 hasConceptScore W4236274738C2778455285 @default.
- W4236274738 hasConceptScore W4236274738C2778583881 @default.
- W4236274738 hasConceptScore W4236274738C2779033008 @default.
- W4236274738 hasConceptScore W4236274738C2781303535 @default.
- W4236274738 hasConceptScore W4236274738C2781362458 @default.
- W4236274738 hasConceptScore W4236274738C509974204 @default.
- W4236274738 hasConceptScore W4236274738C71924100 @default.
- W4236274738 hasConceptScore W4236274738C90924648 @default.
- W4236274738 hasLocation W42362747381 @default.
- W4236274738 hasOpenAccess W4236274738 @default.
- W4236274738 hasPrimaryLocation W42362747381 @default.
- W4236274738 hasRelatedWork W10085251 @default.
- W4236274738 hasRelatedWork W11178581 @default.
- W4236274738 hasRelatedWork W1389656 @default.
- W4236274738 hasRelatedWork W14750688 @default.
- W4236274738 hasRelatedWork W550143 @default.
- W4236274738 hasRelatedWork W5612486 @default.
- W4236274738 hasRelatedWork W5768491 @default.
- W4236274738 hasRelatedWork W5959671 @default.
- W4236274738 hasRelatedWork W7159758 @default.
- W4236274738 hasRelatedWork W7878638 @default.
- W4236274738 isParatext "false" @default.
- W4236274738 isRetracted "false" @default.
- W4236274738 workType "article" @default.