Matches in SemOpenAlex for { <https://semopenalex.org/work/W4236364600> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4236364600 abstract "<sec> <title>BACKGROUND</title> Blockchain technology is emerging as an innovative tool in data and software security. </sec> <sec> <title>OBJECTIVE</title> This study aims to explore the role of blockchain in supporting clinical trials data management and develop a proof-of-concept implementation of a patient-facing and researcher-facing system. </sec> <sec> <title>METHODS</title> Blockchain-based Smart Contracts were built using the Ethereum platform. </sec> <sec> <title>RESULTS</title> We described BlockTrial, a system that uses a Web-based interface to allow users to run trials-related Smart Contracts on an Ethereum network. Functions allow patients to grant researchers access to their data and allow researchers to submit queries for data that are stored off chain. As a type of distributed ledger, the system generates a durable and transparent log of these and other transactions. BlockTrial could be used to increase the trustworthiness of data collected during clinical research with benefits to researchers, regulators, and drug companies alike. In addition, the system could empower patients to become more active and fully informed partners in research. </sec> <sec> <title>CONCLUSIONS</title> Blockchain technology presents an opportunity to address some of the common threats to the integrity of data collected in clinical trials and ensure that the analysis of these data comply with prespecified plans. Further technical work is needed to add additional functions. Policies must be developed to determine the optimal models for participation in the system by its various stakeholders. </sec>" @default.
- W4236364600 created "2022-05-12" @default.
- W4236364600 creator A5049754266 @default.
- W4236364600 creator A5054809800 @default.
- W4236364600 creator A5069031048 @default.
- W4236364600 creator A5081016803 @default.
- W4236364600 date "2018-08-15" @default.
- W4236364600 modified "2023-10-18" @default.
- W4236364600 title "Using Blockchain Technology to Manage Clinical Trials Data: A Proof-of-Concept Study (Preprint)" @default.
- W4236364600 cites W1963526469 @default.
- W4236364600 cites W2011730055 @default.
- W4236364600 cites W2043658255 @default.
- W4236364600 cites W2068444463 @default.
- W4236364600 cites W2093274439 @default.
- W4236364600 cites W2100267603 @default.
- W4236364600 cites W2118070418 @default.
- W4236364600 cites W2164005910 @default.
- W4236364600 cites W2531564265 @default.
- W4236364600 cites W2538325702 @default.
- W4236364600 cites W2582723196 @default.
- W4236364600 cites W2616934625 @default.
- W4236364600 cites W2738959495 @default.
- W4236364600 cites W2751179194 @default.
- W4236364600 cites W2754931682 @default.
- W4236364600 cites W2797814249 @default.
- W4236364600 cites W2800976054 @default.
- W4236364600 cites W2802653242 @default.
- W4236364600 doi "https://doi.org/10.2196/preprints.11949" @default.
- W4236364600 hasPublicationYear "2018" @default.
- W4236364600 type Work @default.
- W4236364600 citedByCount "2" @default.
- W4236364600 countsByYear W42363646002020 @default.
- W4236364600 countsByYear W42363646002023 @default.
- W4236364600 crossrefType "posted-content" @default.
- W4236364600 hasAuthorship W4236364600A5049754266 @default.
- W4236364600 hasAuthorship W4236364600A5054809800 @default.
- W4236364600 hasAuthorship W4236364600A5069031048 @default.
- W4236364600 hasAuthorship W4236364600A5081016803 @default.
- W4236364600 hasBestOaLocation W42363646001 @default.
- W4236364600 hasConcept C111919701 @default.
- W4236364600 hasConcept C124101348 @default.
- W4236364600 hasConcept C124978682 @default.
- W4236364600 hasConcept C136764020 @default.
- W4236364600 hasConcept C142724271 @default.
- W4236364600 hasConcept C1668388 @default.
- W4236364600 hasConcept C2522767166 @default.
- W4236364600 hasConcept C2779687700 @default.
- W4236364600 hasConcept C2779950589 @default.
- W4236364600 hasConcept C33762810 @default.
- W4236364600 hasConcept C38652104 @default.
- W4236364600 hasConcept C41008148 @default.
- W4236364600 hasConcept C43169469 @default.
- W4236364600 hasConcept C535046627 @default.
- W4236364600 hasConcept C71924100 @default.
- W4236364600 hasConceptScore W4236364600C111919701 @default.
- W4236364600 hasConceptScore W4236364600C124101348 @default.
- W4236364600 hasConceptScore W4236364600C124978682 @default.
- W4236364600 hasConceptScore W4236364600C136764020 @default.
- W4236364600 hasConceptScore W4236364600C142724271 @default.
- W4236364600 hasConceptScore W4236364600C1668388 @default.
- W4236364600 hasConceptScore W4236364600C2522767166 @default.
- W4236364600 hasConceptScore W4236364600C2779687700 @default.
- W4236364600 hasConceptScore W4236364600C2779950589 @default.
- W4236364600 hasConceptScore W4236364600C33762810 @default.
- W4236364600 hasConceptScore W4236364600C38652104 @default.
- W4236364600 hasConceptScore W4236364600C41008148 @default.
- W4236364600 hasConceptScore W4236364600C43169469 @default.
- W4236364600 hasConceptScore W4236364600C535046627 @default.
- W4236364600 hasConceptScore W4236364600C71924100 @default.
- W4236364600 hasLocation W42363646001 @default.
- W4236364600 hasLocation W42363646002 @default.
- W4236364600 hasOpenAccess W4236364600 @default.
- W4236364600 hasPrimaryLocation W42363646001 @default.
- W4236364600 hasRelatedWork W2890999343 @default.
- W4236364600 hasRelatedWork W2974298552 @default.
- W4236364600 hasRelatedWork W3021375942 @default.
- W4236364600 hasRelatedWork W3096305091 @default.
- W4236364600 hasRelatedWork W3124350689 @default.
- W4236364600 hasRelatedWork W3157813756 @default.
- W4236364600 hasRelatedWork W3214573662 @default.
- W4236364600 hasRelatedWork W4206573979 @default.
- W4236364600 hasRelatedWork W4366965035 @default.
- W4236364600 hasRelatedWork W4385366921 @default.
- W4236364600 isParatext "false" @default.
- W4236364600 isRetracted "false" @default.
- W4236364600 workType "article" @default.