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- W4236534577 abstract "P elements are cut-and-paste transposons in the genomes of Drosophila melanogaster and several other Drosophila species. The transposition of these elements is catalyzed by an enzyme, the transposase, which is encoded by the structurally complete members of the P-element family. This enzyme is naturally produced only in germline tissues. When activated, P elements cause sterility and high frequencies of mutation and chromosome breakage. These abnormalities are seen in the hybrid offspring of crosses between females that do not have P elements in their genomes and males that do. This syndrome of germline abnormalities is called hybrid dysgenesis. In the germ line, P-element activity is repressed by small RNAs that are inherited from P-bearing females – a form of regulation called the P cytotype. In research, P elements are routinely used as genetic tools to mutate genes, break chromosomes, and create transgenic strains of Drosophila." @default.
- W4236534577 created "2022-05-12" @default.
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- W4236534577 date "2013-01-01" @default.
- W4236534577 modified "2023-09-27" @default.
- W4236534577 title "P Elements" @default.
- W4236534577 doi "https://doi.org/10.1016/b978-0-12-374984-0.01112-8" @default.
- W4236534577 hasPublicationYear "2013" @default.
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