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- W4236690805 abstract "Empfindlich: Isotopencodierte Affinitätsmarker (ICATs) sind vielseitige Sonden zur Untersuchung von dynamischen Proteinstrukturen (Footprinting). Um ein effektives Testsystem zu erhalten, wurde eine Serie von ICAT-Reagentien entworfen (siehe Bild), deren Alkylierungsgeschwindigkeiten fünf Größenordnungen überspannen. Mit ihnen konnte eine beispiellose Auswahl von Cys-Resten aufgespürt werden, darunter auch solche, die tief im Proteinkern vergraben und an moderat affinen Protein-Protein-Wechselwirkungen beteiligt sind. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W4236690805 date "2008-11-26" @default.
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- W4236690805 title "Isotope‐Coded Affinity Tags with Tunable Reactivities for Protein Footprinting" @default.
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