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- W4237243386 abstract "Tuberculosis (TB) remains a global health security risk and a major cause of morbidity and mortality. The TB epidemic continues unabated, with 9.6 million infections occurring globally in 2014, coupled with an overall 1.5 million deaths (1). Of these infected individuals, 12% were found to have concomitant human immunodeficiency virus (HIV) infection. While prevalence and incidence vary significantly across countries, the annual global incidence has decreased year after year since 2000 by an average of 1.5%. Twenty-two high-burden countries (HBCs) are responsible for 80% of all estimated incident TB cases. Alarmingly, one-third of all TB cases remain undiagnosed (or underreported), and the statistics are significantly worse for drug-resistant TB (2). Reported multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) cases are inevitably on the rise as increased numbers of individuals are being diagnosed and treated, adherence remains unchecked or unsuccessful, and infection control practices remain suboptimal. Nearly half a million MDR-TB cases are diagnosed annually, representing less than a quarter of estimated incident cases (2). There is significant work to be done to improve detection of drug-resistant TB and to ensure linkage to appropriate care of patients." @default.
- W4237243386 created "2022-05-12" @default.
- W4237243386 creator A5025515812 @default.
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- W4237243386 creator A5056139536 @default.
- W4237243386 creator A5075030692 @default.
- W4237243386 creator A5082846351 @default.
- W4237243386 date "2017-09-05" @default.
- W4237243386 modified "2023-09-25" @default.
- W4237243386 title "Impact of the GeneXpert MTB/RIF Technology on Tuberculosis Control" @default.
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- W4237243386 doi "https://doi.org/10.1128/9781555819569.ch18" @default.
- W4237243386 hasPublicationYear "2017" @default.
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