Matches in SemOpenAlex for { <https://semopenalex.org/work/W4237354007> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W4237354007 endingPage "152" @default.
- W4237354007 startingPage "152" @default.
- W4237354007 abstract "Abstract The active form of vitamin D, 1α,25-dihydroxyvitamin D3, is critical for the regulation of serum calcium and phosphorus levels that in turn support bone mineralization and neuromuscular activity. It is well known that vitamin D deficiency causes rachitic/osteomalacic myopathy and cardiac disorder and the provision of vitamin D can reverse the symptoms. However, the underlying mechanisms remain unclear. The question of whether the vitamin D receptor is found in muscle has been debated but not settled. We recently studied all available antibodies against the vitamin D receptor and found that most antibodies used detect proteins other than the vitamin D receptor, and therefore, the utility of these antibodies may generate the false-positive results. Using antibodies that do not detect proteins in tissues from vitamin D receptor null mice, we have developed a specific and sensitive immunohistochemical assay. The results from this investigation show that the vitamin D receptor is undetectable in skeletal, cardiac, and smooth muscle, suggesting that the function of vitamin D on muscle is either of an indirect nature or does not involve the known receptor." @default.
- W4237354007 created "2022-05-12" @default.
- W4237354007 creator A5003873771 @default.
- W4237354007 creator A5064567218 @default.
- W4237354007 date "2011-02-01" @default.
- W4237354007 modified "2023-10-17" @default.
- W4237354007 title "Is the Vitamin D Receptor Found in Muscle?" @default.
- W4237354007 doi "https://doi.org/10.1210/edrv.32.1.zef152b" @default.
- W4237354007 hasPublicationYear "2011" @default.
- W4237354007 type Work @default.
- W4237354007 citedByCount "1" @default.
- W4237354007 countsByYear W42373540072015 @default.
- W4237354007 crossrefType "journal-article" @default.
- W4237354007 hasAuthorship W4237354007A5003873771 @default.
- W4237354007 hasAuthorship W4237354007A5064567218 @default.
- W4237354007 hasBestOaLocation W42373540071 @default.
- W4237354007 hasConcept C124490489 @default.
- W4237354007 hasConcept C126322002 @default.
- W4237354007 hasConcept C134018914 @default.
- W4237354007 hasConcept C153639570 @default.
- W4237354007 hasConcept C159654299 @default.
- W4237354007 hasConcept C170493617 @default.
- W4237354007 hasConcept C179639408 @default.
- W4237354007 hasConcept C203014093 @default.
- W4237354007 hasConcept C204232928 @default.
- W4237354007 hasConcept C2776940978 @default.
- W4237354007 hasConcept C2778996579 @default.
- W4237354007 hasConcept C2779740938 @default.
- W4237354007 hasConcept C2779959927 @default.
- W4237354007 hasConcept C71924100 @default.
- W4237354007 hasConcept C86803240 @default.
- W4237354007 hasConceptScore W4237354007C124490489 @default.
- W4237354007 hasConceptScore W4237354007C126322002 @default.
- W4237354007 hasConceptScore W4237354007C134018914 @default.
- W4237354007 hasConceptScore W4237354007C153639570 @default.
- W4237354007 hasConceptScore W4237354007C159654299 @default.
- W4237354007 hasConceptScore W4237354007C170493617 @default.
- W4237354007 hasConceptScore W4237354007C179639408 @default.
- W4237354007 hasConceptScore W4237354007C203014093 @default.
- W4237354007 hasConceptScore W4237354007C204232928 @default.
- W4237354007 hasConceptScore W4237354007C2776940978 @default.
- W4237354007 hasConceptScore W4237354007C2778996579 @default.
- W4237354007 hasConceptScore W4237354007C2779740938 @default.
- W4237354007 hasConceptScore W4237354007C2779959927 @default.
- W4237354007 hasConceptScore W4237354007C71924100 @default.
- W4237354007 hasConceptScore W4237354007C86803240 @default.
- W4237354007 hasIssue "1" @default.
- W4237354007 hasLocation W42373540071 @default.
- W4237354007 hasOpenAccess W4237354007 @default.
- W4237354007 hasPrimaryLocation W42373540071 @default.
- W4237354007 hasRelatedWork W12992013 @default.
- W4237354007 hasRelatedWork W17166117 @default.
- W4237354007 hasRelatedWork W19177983 @default.
- W4237354007 hasRelatedWork W20664381 @default.
- W4237354007 hasRelatedWork W22725323 @default.
- W4237354007 hasRelatedWork W23032388 @default.
- W4237354007 hasRelatedWork W24370168 @default.
- W4237354007 hasRelatedWork W28541829 @default.
- W4237354007 hasRelatedWork W32277516 @default.
- W4237354007 hasRelatedWork W39069354 @default.
- W4237354007 hasVolume "32" @default.
- W4237354007 isParatext "false" @default.
- W4237354007 isRetracted "false" @default.
- W4237354007 workType "article" @default.