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- W4237428842 abstract "The majority of lymphocytic infiltrates in the skin are of T cell derivation and reactive in nature, manifesting neither significant cytologic nor architectural atypia. The basis of benign T cell lymphocytic infiltration is one that is immunologically driven, reflecting a type IV cellular cytotoxic interface dermatitis, delayed-type hypersensitivity, and antibody-dependent cellular immunity. The hallmarks of spongiotic dermatitis are exocytosis of lymphocytes into an epidermis that shows spongiosis with variable vesiculation and a parakeratotic scale. The eczematous component encompasses changes that are virtually identical to those described for acute allergic contact dermatitis, including marked spongiosis with exocytosis of lymphocytes and eosinophils and Langerhans cell- and eosinophil-containing intraepidermal vesicles. There are two broad categories of interface dermatitis, namely cell-poor or vacuolar interface dermatitis and cell-rich or lichenoid dermatitis. In the interface dermatitis of collagen vascular disease, hyper- and parakeratosis are frequent." @default.
- W4237428842 created "2022-05-12" @default.
- W4237428842 date "2016-01-01" @default.
- W4237428842 modified "2023-09-29" @default.
- W4237428842 title "Benign Lymphocytic Infiltrates" @default.
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- W4237428842 doi "https://doi.org/10.1002/9781118776193.ch4" @default.
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