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- W4237477276 abstract "<h3>In Reply.—</h3> Drs West and Russell believe that any nicotine dependence in our subjects was present prior to their use of nicotine gum; ie, nicotine gum maintained an old dependence rather than caused a new one. We agree that this is possible, and that was the reason for using the phrase develop (or maintain) in the article. We disagree that it can be said to be true for<i>all</i>of our subjects since not all smokers are physically dependent on nicotine (ie, have withdrawal upon cessation of smoking that is relieved by nicotine).<sup>1,2</sup> Drs West and Russell imply that the generalizability of our results is limited because we used a highly selected sample. In fact, unlike their study, which included only smokers who had used the gum for at least 12 months, five of our eight subjects had used the gum for less than six months and three had" @default.
- W4237477276 created "2022-05-12" @default.
- W4237477276 date "1986-12-19" @default.
- W4237477276 modified "2023-09-27" @default.
- W4237477276 doi "https://doi.org/10.1001/jama.256.23.3215" @default.
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