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- W4237532018 abstract "Introduction The History of Immunomodulators What is an Immunoregulator? Why Modulate the Immune System? How can the Immune System be Modulated? Immune Regulators as Products Production of Immune Regulators Product Quality and Safety Issues Product Quality and Safety Operator Safety Control of Material Production Methods Isolate Material from Natural Sources such as Blood Use Natural Producer Cell Lines Produce Recombinant Cell Lines (Animal Cell or Microbial) Use Gene Therapy Vectors to Introduce Genes into Target Cells Process Design Development and Operation Cloning Selection Criteria for Cell Lines Stability Productivity Growth Kinetics and Subculture Regime Oxygen Utilization Nutrient Utilization Patterns Culture Media Sterilization Serum Medium Formulations pH Buffering Osmolality and Feed Media Intellectual Property Supply and use of Media Properties of a Cell Culture Medium Culture Media and Cell Line Development Handling of Cell Lines Process Development Generic Process Development Modify Physical Conditions Process Control and Optimization Product Concentration and Product Recovery Process Monitoring Safety Issues Production of Seed Cultures for the Production Vessels Outer Limits Validation Process Validation and Consistency Batches Product Stability Summary References" @default.
- W4237532018 created "2022-05-12" @default.
- W4237532018 creator A5058759071 @default.
- W4237532018 date "2010-04-15" @default.
- W4237532018 modified "2023-10-10" @default.
- W4237532018 title "Immunoregulators" @default.
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- W4237532018 doi "https://doi.org/10.1002/9780470054581.eib609" @default.
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