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• W4237584711 abstract "A panel of novel monoclonal antibodies was tested on the human entorhinal cortex for the recognition of age- and disease-related changes of neurofilament proteins (NF). Several antibodies identified phosphorylated NF-H subunit, which occurred preferentially in those aged between 60 and 80 years and were localized in degenerating neurons. Such neurons also contained neurofibrillary tangles, but neurofilament aggregates did not co-localize with tangles, nor did the quantity nor the number of NF-positive neurons correlate with the severity of Alzheimer's disease. This points to a susceptibility of NF in a subset of neurons for phosphor-ylation- and metabolically related morphological changes during neurodegeneration." @default.
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• W4237584711 date "2003-05-01" @default.
• W4237584711 modified "2023-10-03" @default.
• W4237584711 title "Differential subcellular localization of phosphorylated neurofilament and tau proteins in degenerating neurons of the human entorhinal cortex" @default.
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• W4237584711 doi "https://doi.org/10.1097/00001756-200305230-00005" @default.
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