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- W4237642911 abstract "A number of accomplishments have been made during the term of this grant. These include both technical aspects of the project, and developments associated with commercial development of the MAGIC- LC/MS interface. Technical advances have been made through a number of detailed studies of fundamental processes occurring with the interface. These have led to substantial improvements in the performance of the interface many of which are detailed below. Of particular importance has been a major improvement in detection capabilities. At beginning of this grant period, sensitivity for many compounds was in the high {mu}g to low mg range. Presently, full-scan (40-400 daltons) electron impacts mass spectra may be obtained for many compounds with typically 10--50 ng of material injected on column. Selected ion monitoring gives detection limits in the range of 100--1000 pg. These figures are particularly noteworthy because they represent values which fall between 3--10x the lowest detection limits possible with the same instrument when used in a GC/MS mode." @default.
- W4237642911 created "2022-05-12" @default.
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- W4237642911 date "1989-05-01" @default.
- W4237642911 modified "2023-09-26" @default.
- W4237642911 title "Fundamental studies with a monodisperse aerosol-based liquid chromatography/mass spectrometry interface (MAGIC-LC/MS)" @default.
- W4237642911 doi "https://doi.org/10.2172/6963245" @default.
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