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- W4237660900 abstract "Most randomized clinical trials are designed to demonstrate benefit of experimental versus standard treatment. For ethical and economic reasons, it is important to stop a trial early for “futility” if there is no longer a reasonable chance that the experimental arm can be shown to be definitively better than the standard arm. Futility monitoring has become a widely accepted component of clinical trial methodology. We provide a review of commonly used futility procedures and discuss practical aspects of their implementation." @default.
- W4237660900 created "2022-05-12" @default.
- W4237660900 creator A5051819886 @default.
- W4237660900 date "2013-05-24" @default.
- W4237660900 modified "2023-09-26" @default.
- W4237660900 title "Futility Analysis" @default.
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- W4237660900 doi "https://doi.org/10.1002/0471667196.ess7171" @default.
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