Matches in SemOpenAlex for { <https://semopenalex.org/work/W4237764385> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W4237764385 endingPage "70" @default.
- W4237764385 startingPage "69" @default.
- W4237764385 abstract "Respiratory rhythm generation depends on a complex interaction between synaptic and membrane properties of functionally defined neurons. To gain a better understanding of how inhibitory and excitatory synaptic inputs lead to the generation of the respiratory rhythm we analyzed the depolarization pattern of respiratory neurons that were recorded in the transverse slice preparation of mice (P8–22) and the in vivo adult cat. Using voltage-clamp recordings from respiratory neurons and specific antagonists for inhibitory synaptic transmission we demonstrate under in vitro conditions, that inspiratory (n=7) and post-inspiratory neurons (n=13) received concurrent glycinergic and glutamatergic synaptic input during inspiration. A similar conclusion was gained with chloride injections into in vivo respiratory neurons. The inhibitory input was essential not only for generating the characteristic depolarization pattern of respiratory neurons, but also for switching the respiratory rhythm between inspiration and post-inspiration. The generation of the depolarization pattern depends also on intrinsic membrane properties. Negative current injections reveal that excitatory synaptic input was amplified by intrinsic bursting properties in some inspiratory neurons (n=4) recorded in vitro. Although such properties have not been described under in vivo conditions our findings suggest that with respect to inspiratory, post-inspiratory and late-inspiratory neurons, the principle network organization is similar under both in vitro and in vivo conditions." @default.
- W4237764385 created "2022-05-12" @default.
- W4237764385 date "1997-11-01" @default.
- W4237764385 modified "2023-10-17" @default.
- W4237764385 title "Editorial" @default.
- W4237764385 doi "https://doi.org/10.1016/s0034-5687(97)00073-x" @default.
- W4237764385 hasPublicationYear "1997" @default.
- W4237764385 type Work @default.
- W4237764385 citedByCount "0" @default.
- W4237764385 crossrefType "journal-article" @default.
- W4237764385 hasConcept C105702510 @default.
- W4237764385 hasConcept C112592302 @default.
- W4237764385 hasConcept C12554922 @default.
- W4237764385 hasConcept C150903083 @default.
- W4237764385 hasConcept C169760540 @default.
- W4237764385 hasConcept C170493617 @default.
- W4237764385 hasConcept C17077164 @default.
- W4237764385 hasConcept C185263204 @default.
- W4237764385 hasConcept C195221683 @default.
- W4237764385 hasConcept C200170125 @default.
- W4237764385 hasConcept C207001950 @default.
- W4237764385 hasConcept C2780648746 @default.
- W4237764385 hasConcept C29694410 @default.
- W4237764385 hasConcept C4141045 @default.
- W4237764385 hasConcept C534529494 @default.
- W4237764385 hasConcept C55493867 @default.
- W4237764385 hasConcept C61174792 @default.
- W4237764385 hasConcept C86803240 @default.
- W4237764385 hasConceptScore W4237764385C105702510 @default.
- W4237764385 hasConceptScore W4237764385C112592302 @default.
- W4237764385 hasConceptScore W4237764385C12554922 @default.
- W4237764385 hasConceptScore W4237764385C150903083 @default.
- W4237764385 hasConceptScore W4237764385C169760540 @default.
- W4237764385 hasConceptScore W4237764385C170493617 @default.
- W4237764385 hasConceptScore W4237764385C17077164 @default.
- W4237764385 hasConceptScore W4237764385C185263204 @default.
- W4237764385 hasConceptScore W4237764385C195221683 @default.
- W4237764385 hasConceptScore W4237764385C200170125 @default.
- W4237764385 hasConceptScore W4237764385C207001950 @default.
- W4237764385 hasConceptScore W4237764385C2780648746 @default.
- W4237764385 hasConceptScore W4237764385C29694410 @default.
- W4237764385 hasConceptScore W4237764385C4141045 @default.
- W4237764385 hasConceptScore W4237764385C534529494 @default.
- W4237764385 hasConceptScore W4237764385C55493867 @default.
- W4237764385 hasConceptScore W4237764385C61174792 @default.
- W4237764385 hasConceptScore W4237764385C86803240 @default.
- W4237764385 hasIssue "2-3" @default.
- W4237764385 hasLocation W42377643851 @default.
- W4237764385 hasOpenAccess W4237764385 @default.
- W4237764385 hasPrimaryLocation W42377643851 @default.
- W4237764385 hasRelatedWork W1079267665 @default.
- W4237764385 hasRelatedWork W1995189077 @default.
- W4237764385 hasRelatedWork W2041870126 @default.
- W4237764385 hasRelatedWork W2094353622 @default.
- W4237764385 hasRelatedWork W2116306030 @default.
- W4237764385 hasRelatedWork W3014191536 @default.
- W4237764385 hasRelatedWork W3086570168 @default.
- W4237764385 hasRelatedWork W3152876215 @default.
- W4237764385 hasRelatedWork W4295874224 @default.
- W4237764385 hasRelatedWork W4321095294 @default.
- W4237764385 hasVolume "110" @default.
- W4237764385 isParatext "false" @default.
- W4237764385 isRetracted "false" @default.
- W4237764385 workType "editorial" @default.