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- W4237777605 abstract "Salbutamol sulphate nebules is considered as the most rapid effective route ofadministration for treatment of acute attacks of asthma .This study was carried out to formulate a stable formula of salbutamol nebulescontaining 0.1% (2.5mg / 2.5ml) of the active ingredient in a buffered solution .Stability study in different buffers at pH 3 showed that the longest shelf life wasequal to 3.5 years for formula F .In addition the bioequivalency of this formulaincomparison to ventolin® nebules was measured and it was equal to (± 5.2) %.Also it was found that there was no significant difference between the formulaand ventolin® nebules regarding their pharmacokinetic parameters which includeelimination rate constant, elimination t 0.5 and amount of the unchanged drug excretedin urine, 30 min. after administration (p<0.05) . This study may suggest that theprepared formula could be used successfully in the preparation of salbutamol sulphatenebules." @default.
- W4237777605 created "2022-05-12" @default.
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- W4237777605 date "2017-03-31" @default.
- W4237777605 modified "2023-10-17" @default.
- W4237777605 title "Formulation, Stability and Bioequivalency Study of Prepared Salbutamol Sulphate Nebules." @default.
- W4237777605 doi "https://doi.org/10.31351/vol14iss1pp65-74" @default.
- W4237777605 hasPublicationYear "2017" @default.
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