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- W4238128843 endingPage "340" @default.
- W4238128843 startingPage "333" @default.
- W4238128843 abstract "Purpose of review Although cluster headache has traditionally been thought of as a vascular headache disorder, its periodicity suggests an involvement of central areas such as the hypothalamus. This review covers the past 3 years, which have seen remarkable progress in understanding the pathophysiology of circadian headache syndromes and have brought exciting news. Recent findings As more cluster headache patients are seen by headache specialists, new forms of this well-defined primary headache syndrome are being identified. In addition, we discuss recent findings with regard to abnormalities in the secretion of hormones, genetic influences, neuroimaging of cluster headache attacks, and the use of newer substances as preventive therapy in cluster headache. Summary We have entered a new diagnostic and therapeutic era in primary headache disorders. In recent reports, the use of deep brain stimulation of the hypothalamus has enabled intractable chronic cluster headache patients to be successfully operated upon. Further research in this field is urgently needed and the recent possibility of combining deep brain stimulation with positron emission tomography will certainly help to unravel the brain circuitry implicated in stimulation-produced analgesia. The time has come to use the evidence for a disorder of circadian rhythm in cluster headache to further the development of chronobiotics in the treatment of this disorder." @default.
- W4238128843 created "2022-05-12" @default.
- W4238128843 creator A5003359125 @default.
- W4238128843 creator A5009170730 @default.
- W4238128843 date "2003-06-01" @default.
- W4238128843 modified "2023-10-10" @default.
- W4238128843 title "Update on cluster headache" @default.
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