Matches in SemOpenAlex for { <https://semopenalex.org/work/W4238143630> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W4238143630 abstract "Abstract Background To examine the relation between inflammatory potential of diet and incident knee osteoarthritis (OA) and the role of BMI in the association of interest. Methods In the Osteoarthritis Initiative, the energy-adjusted dietary inflammatory index (E-DII TM ) scores were calculated based on the Block Brief 2000 Food Frequency Questionnaire and categorized into sex-specific quartiles. Outcomes were incident: (1) radiographic knee OA (ROA) (i.e., a KL grade ≥2), (2) symptomatic knee OA (SxOA) (i.e., a combination of a frequent knee pain and ROA). We fitted generalized estimating equation models to examine the association between E-DII scores and incident knee OA. We performed mediation analyses to assess potential mediation by BMI in the DII-OA relation. Results Over a 48-month follow-up period, 232 and 978 knees developed ROA and SxOA, respectively. Compared with the lowest (most anti-inflammatory) E-DII quartile, the odds ratio (OR) of incident ROA for the highest (most pro-inflammatory) E-DII quartile was 1.73 (95% confidence interval (CI): 1.15 to 2.62, P trend = 0.007). The corresponding OR for SxOA was 1.43 (95% CI: 1.16 to 1.76, P trend = 0.001). The DII-OA association was significantly mediated via BMI with an indirect effect of 1.08 (95% CI: 1.04,1.13) for ROA and 1.13 (95% CI: 1.09, 1.16) for SxOA, accounting for 20.4% and 44.5% of total effect, respectively. Conclusions A higher inflammatory potential of diet increased the risk of knee OA. The association was significantly mediated via BMI. Targeting inflammatory potential of diet may be beneficial to reduce risk of knee OA." @default.
- W4238143630 created "2022-05-12" @default.
- W4238143630 creator A5002637741 @default.
- W4238143630 creator A5032946070 @default.
- W4238143630 creator A5038298202 @default.
- W4238143630 creator A5041571735 @default.
- W4238143630 creator A5047585545 @default.
- W4238143630 creator A5052663273 @default.
- W4238143630 creator A5070347565 @default.
- W4238143630 creator A5083201788 @default.
- W4238143630 creator A5088213590 @default.
- W4238143630 date "2020-08-18" @default.
- W4238143630 modified "2023-09-27" @default.
- W4238143630 title "Inflammatory potential of diet and risk of incident knee osteoarthritis: a prospective cohort study" @default.
- W4238143630 doi "https://doi.org/10.21203/rs.3.rs-31057/v2" @default.
- W4238143630 hasPublicationYear "2020" @default.
- W4238143630 type Work @default.
- W4238143630 citedByCount "0" @default.
- W4238143630 crossrefType "posted-content" @default.
- W4238143630 hasAuthorship W4238143630A5002637741 @default.
- W4238143630 hasAuthorship W4238143630A5032946070 @default.
- W4238143630 hasAuthorship W4238143630A5038298202 @default.
- W4238143630 hasAuthorship W4238143630A5041571735 @default.
- W4238143630 hasAuthorship W4238143630A5047585545 @default.
- W4238143630 hasAuthorship W4238143630A5052663273 @default.
- W4238143630 hasAuthorship W4238143630A5070347565 @default.
- W4238143630 hasAuthorship W4238143630A5083201788 @default.
- W4238143630 hasAuthorship W4238143630A5088213590 @default.
- W4238143630 hasBestOaLocation W42381436301 @default.
- W4238143630 hasConcept C126322002 @default.
- W4238143630 hasConcept C142724271 @default.
- W4238143630 hasConcept C156957248 @default.
- W4238143630 hasConcept C17744445 @default.
- W4238143630 hasConcept C179420905 @default.
- W4238143630 hasConcept C188816634 @default.
- W4238143630 hasConcept C199539241 @default.
- W4238143630 hasConcept C201903717 @default.
- W4238143630 hasConcept C204787440 @default.
- W4238143630 hasConcept C2776164576 @default.
- W4238143630 hasConcept C2779279471 @default.
- W4238143630 hasConcept C2780221984 @default.
- W4238143630 hasConcept C44249647 @default.
- W4238143630 hasConcept C68443243 @default.
- W4238143630 hasConcept C71924100 @default.
- W4238143630 hasConcept C72563966 @default.
- W4238143630 hasConceptScore W4238143630C126322002 @default.
- W4238143630 hasConceptScore W4238143630C142724271 @default.
- W4238143630 hasConceptScore W4238143630C156957248 @default.
- W4238143630 hasConceptScore W4238143630C17744445 @default.
- W4238143630 hasConceptScore W4238143630C179420905 @default.
- W4238143630 hasConceptScore W4238143630C188816634 @default.
- W4238143630 hasConceptScore W4238143630C199539241 @default.
- W4238143630 hasConceptScore W4238143630C201903717 @default.
- W4238143630 hasConceptScore W4238143630C204787440 @default.
- W4238143630 hasConceptScore W4238143630C2776164576 @default.
- W4238143630 hasConceptScore W4238143630C2779279471 @default.
- W4238143630 hasConceptScore W4238143630C2780221984 @default.
- W4238143630 hasConceptScore W4238143630C44249647 @default.
- W4238143630 hasConceptScore W4238143630C68443243 @default.
- W4238143630 hasConceptScore W4238143630C71924100 @default.
- W4238143630 hasConceptScore W4238143630C72563966 @default.
- W4238143630 hasLocation W42381436301 @default.
- W4238143630 hasLocation W42381436302 @default.
- W4238143630 hasLocation W42381436303 @default.
- W4238143630 hasOpenAccess W4238143630 @default.
- W4238143630 hasPrimaryLocation W42381436301 @default.
- W4238143630 hasRelatedWork W1015868 @default.
- W4238143630 hasRelatedWork W10510644 @default.
- W4238143630 hasRelatedWork W10730906 @default.
- W4238143630 hasRelatedWork W1321646 @default.
- W4238143630 hasRelatedWork W15311529 @default.
- W4238143630 hasRelatedWork W20482656 @default.
- W4238143630 hasRelatedWork W4346409 @default.
- W4238143630 hasRelatedWork W6231026 @default.
- W4238143630 hasRelatedWork W6668650 @default.
- W4238143630 hasRelatedWork W7726188 @default.
- W4238143630 isParatext "false" @default.
- W4238143630 isRetracted "false" @default.
- W4238143630 workType "article" @default.