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- W4238156716 abstract "Vulval squamous cell carcinoma is mainly diagnosed in elderly women with a mean age at diagnosis of approximately 70 years. Risk factors associated with human papillomavirus (HPV) infection include early age at first intercourse, multiple sexual partners, human immunodeficiency virus (HIV) infection and cigarette smoking. Two independent pathways of vulvar carcinogenesis currently exist, both with their own premalignant lesions and invasive histologic forms. One type is related to lichen sclerosis (LS) and the second type is related to HPV infection. The second type consists of mainly nonkeratinizing carcinomas and affects primarily younger women. A unilateral lymphadenectomy is recommended for women with a lesion > 1 cm from the vulvar midline and no palpable groin nodes on examination or abnormal lymph nodes on ultrasound. Vulval squamous cell carcinoma often coexist with premalignant undifferentiated vulval intraepithelial neoplasia (uVIN) or differentiated VIN (dVIN)." @default.
- W4238156716 created "2022-05-12" @default.
- W4238156716 date "2017-01-14" @default.
- W4238156716 modified "2023-10-17" @default.
- W4238156716 title "Vulval Squamous Cell Carcinoma" @default.
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- W4238156716 doi "https://doi.org/10.1002/9781119146087.ch21" @default.
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