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- W4238258672 abstract "This chapter focuses on solid tumors and how they can be treated. Solid tumors, lymphomas, and leukemias represent a widely diverse array of cancers. Until recently, the general approach to treating all of them was to administer cytotoxic anticancer drugs that damage proliferating cells by interfering with mitosis and other essential steps in cellular replication. Localized solid tumors are largely treated by surgical resection and radiotherapy, with cytotoxic chemotherapy being commonly used adjunctively or in cases of metastatic disease. A major drawback of this approach has been the lack of specificity in that cytotoxic drugs will destroy actively dividing normal cells as well as malignant cells. The “shotgun approach” of using intensive cytotoxic chemotherapies has been the mainstay of cancer treatment for at least 6 decades. The chapter concludes that in addition to the tissue damage and immunomodulating effects of anticancer drugs, it should be remembered that cancers themselves may increase the chances for infection." @default.
- W4238258672 created "2022-05-12" @default.
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- W4238258672 date "2016-02-01" @default.
- W4238258672 modified "2023-09-27" @default.
- W4238258672 title "An Introduction" @default.
- W4238258672 doi "https://doi.org/10.1093/med/9780199938568.003.0100" @default.
- W4238258672 hasPublicationYear "2016" @default.
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