Matches in SemOpenAlex for { <https://semopenalex.org/work/W4238306064> ?p ?o ?g. }
- W4238306064 endingPage "2495" @default.
- W4238306064 startingPage "2491" @default.
- W4238306064 abstract "Abstract A scalable, one‐pot, enantioselective catalytic synthesis of 2‐pyrazolines from beta‐substituted enones and hydrazines is described. Pivoting on a two‐stage catalytic Michael addition/condensation strategy, the use of an aldehyde to generate a suitable hydrazone derivative of the hydrazine was found to be key for curtailing background reactivity and tuning the catalyst‐controlled enantioselectivity. The new synthetic method is easy to perform, uses a new and readily prepared cinchona‐derived bifunctional catalyst, is broad in scope, and tolerates a range of functionalities with high enantioselectivity (up to >99:1 e.r.). The significant scalability of this methodology was demonstrated with the synthesis of more than 80 grams of a pyrazoline product with 89 % catalyst recovery." @default.
- W4238306064 created "2022-05-12" @default.
- W4238306064 creator A5001468983 @default.
- W4238306064 creator A5026961894 @default.
- W4238306064 creator A5059540181 @default.
- W4238306064 date "2019-01-24" @default.
- W4238306064 modified "2023-09-25" @default.
- W4238306064 title "One-Pot Catalytic Enantioselective Synthesis of 2-Pyrazolines" @default.
- W4238306064 cites W1964486733 @default.
- W4238306064 cites W1965429588 @default.
- W4238306064 cites W1968211156 @default.
- W4238306064 cites W1973387370 @default.
- W4238306064 cites W1977375280 @default.
- W4238306064 cites W1981075782 @default.
- W4238306064 cites W1983086217 @default.
- W4238306064 cites W1988658955 @default.
- W4238306064 cites W1993938088 @default.
- W4238306064 cites W1994664216 @default.
- W4238306064 cites W1995396482 @default.
- W4238306064 cites W1997161855 @default.
- W4238306064 cites W1999485520 @default.
- W4238306064 cites W2004998386 @default.
- W4238306064 cites W2008304599 @default.
- W4238306064 cites W2020221504 @default.
- W4238306064 cites W2023354455 @default.
- W4238306064 cites W2030035423 @default.
- W4238306064 cites W2031550048 @default.
- W4238306064 cites W2044320182 @default.
- W4238306064 cites W2051614914 @default.
- W4238306064 cites W2062917234 @default.
- W4238306064 cites W2063912619 @default.
- W4238306064 cites W2068564021 @default.
- W4238306064 cites W2071280170 @default.
- W4238306064 cites W2072717022 @default.
- W4238306064 cites W2076539714 @default.
- W4238306064 cites W2076627887 @default.
- W4238306064 cites W2076892344 @default.
- W4238306064 cites W2083314923 @default.
- W4238306064 cites W2110939537 @default.
- W4238306064 cites W2111040418 @default.
- W4238306064 cites W2112656134 @default.
- W4238306064 cites W2119462622 @default.
- W4238306064 cites W2122320928 @default.
- W4238306064 cites W2124218271 @default.
- W4238306064 cites W2133930842 @default.
- W4238306064 cites W2141060509 @default.
- W4238306064 cites W2153326857 @default.
- W4238306064 cites W2156523723 @default.
- W4238306064 cites W2165666769 @default.
- W4238306064 cites W2170656464 @default.
- W4238306064 cites W2279565723 @default.
- W4238306064 cites W2318497202 @default.
- W4238306064 cites W2319125021 @default.
- W4238306064 cites W2323418795 @default.
- W4238306064 cites W2343750596 @default.
- W4238306064 cites W2461688213 @default.
- W4238306064 cites W2518549978 @default.
- W4238306064 cites W2606106163 @default.
- W4238306064 cites W2695325110 @default.
- W4238306064 cites W2792068381 @default.
- W4238306064 cites W2803127873 @default.
- W4238306064 cites W2809829333 @default.
- W4238306064 cites W2950008722 @default.
- W4238306064 cites W2951263088 @default.
- W4238306064 cites W2951927279 @default.
- W4238306064 cites W2952799437 @default.
- W4238306064 cites W4230354686 @default.
- W4238306064 cites W4231798389 @default.
- W4238306064 cites W4232502776 @default.
- W4238306064 cites W4239983470 @default.
- W4238306064 cites W4246753632 @default.
- W4238306064 cites W4256209136 @default.
- W4238306064 cites W2120521341 @default.
- W4238306064 doi "https://doi.org/10.1002/ange.201811471" @default.
- W4238306064 hasPublicationYear "2019" @default.
- W4238306064 type Work @default.
- W4238306064 citedByCount "4" @default.
- W4238306064 countsByYear W42383060642019 @default.
- W4238306064 countsByYear W42383060642021 @default.
- W4238306064 countsByYear W42383060642022 @default.
- W4238306064 crossrefType "journal-article" @default.
- W4238306064 hasAuthorship W4238306064A5001468983 @default.
- W4238306064 hasAuthorship W4238306064A5026961894 @default.
- W4238306064 hasAuthorship W4238306064A5059540181 @default.
- W4238306064 hasBestOaLocation W42383060642 @default.
- W4238306064 hasConcept C146686406 @default.
- W4238306064 hasConcept C161790260 @default.
- W4238306064 hasConcept C178790620 @default.
- W4238306064 hasConcept C185592680 @default.
- W4238306064 hasConcept C21951064 @default.
- W4238306064 hasConcept C2776597398 @default.
- W4238306064 hasConcept C2779825165 @default.
- W4238306064 hasConcept C2780349576 @default.
- W4238306064 hasConcept C2780443040 @default.
- W4238306064 hasConcept C40875361 @default.
- W4238306064 hasConcept C43617362 @default.
- W4238306064 hasConceptScore W4238306064C146686406 @default.
- W4238306064 hasConceptScore W4238306064C161790260 @default.