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• W4238330680 abstract "Abstract Liver transplantation is a treatment modality that is being used with increasing frequency in cases of liver-based metabolic defects. This is a case report of a patient with hemophilia B who was treated since childhood with factor IX replacement for recurrent hemarthroses. Subsequent hepatitis B (HBV) and C (HCV) infection had resulted in the development of chronic active hepatitis, ultimately leading to cirrhosis. Orthotopic liver transplantation performed for end-stage liver disease resulted in a rise in factor IX levels from 2% to 83% of normal values within 24 h post-operatively, and levels remained above 90% of normal values after postoperative day 3 without factor IX replacement. To our knowledge, only two cases of hemophilia B treated by orthotopic liver transplantation have been reported. This procedure has, however, only been implemented in cases of terminal liver insufficiency in hemophiliacs." @default.
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• W4238330680 date "1995-11-01" @default.
• W4238330680 modified "2023-09-26" @default.
• W4238330680 title "Orthotopic liver transplantation in hemophilia B: a case report" @default.
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• W4238330680 doi "https://doi.org/10.1111/j.1432-2277.1995.tb01560.x" @default.
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