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- W4238357619 abstract "Abstract Background: Hymenolepis nana , commonly found parasite in mice colonies maintained under conventional conditions, has zoonotic potential and is characterised by autoinfection and direct life cycle. Results: This study intended to determine parasitic infection rate in laboratory mice. Of the 50 mice, 40.0% were found to be infected with hymenolepidid cestode. Infection rate was higher in males (52.0%) than in females (28.0%). Light and scanning electron microscopic studies of cestode parasite revealed that the worms were medium-sized; had globular scolex with four suckers, a retractable rostellum equipped with 20-30 hooks, and a short unsegmented neck; remaining strobila consisted of immature, mature, and gravid proglottids; irregularly alternating genital pores; lobulated ovary; post-ovarian vitelline gland; and uterus containing ˃200 small eggs in gravid proglottids. Molecular characterisation based on mitochondrial COX1 gene sequence analysis used to confirm taxonomy of the parasite. The parasite showed identity ˃80.0% with other species available in GenBank. High blast scores and low divergence were noted between isolated parasite and previously described H. nana (gb| AP017666.1). Phylogenetic analysis using COX1 sequence place this hymenolepidid species within Cyclophyllidea. Conclusions: The present species was found to be deeply embedded in the genus Hymenolepis with close relationships to other H. nana as a putative sister taxon." @default.
- W4238357619 created "2022-05-12" @default.
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- W4238357619 date "2019-10-01" @default.
- W4238357619 modified "2023-09-27" @default.
- W4238357619 title "Morphological, molecular and pathological appraisal of Hymenolepis nana (Hymenolepididae) infecting laboratory mice Mus musculus" @default.
- W4238357619 doi "https://doi.org/10.21203/rs.2.14737/v1" @default.
- W4238357619 hasPublicationYear "2019" @default.
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