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- W423840912 abstract "This experiment was conducted to determine if changing the amount of total essential amino acids (TEAA) in relation to caloric intake would influence nitrogen metabolism and weight loss during caloric restriction in moderately overweight mature dogs. Six moderately overweight mature female crossbred hounds were fed dry foods varying in their ratio of TEAA:calories (TEAA %: Mcal ME/g; 17.3, 21.0, and 22.3) in a replicated 3 × 3 Latin square design. Total essential amino acids:protein was held constant at approximately 0.4 for all treatments. The periods were 28d; 14 d of ad libitum alimentation followed by 14 d of restriction to 0.75 of maintenance energy requirements for ideal weight. All measurements were made the final 7 d of the restriction. Increasing the TEAA:calorie of the foods linearly increased (P < 0.01) N absorbed and tended (linear P = 0.13) to increase N retention and weight loss (linear P = 0.08). Protein synthesis (measured by 15N-glycine) was not affected but degradation (P= 0.06) and turnover (P = 0.07) tended to be lowest for the intermediate treatment. Plasma urea concentrations and creatinine excretion were not affected. Based on overall positive effects on weight loss and N metabolism the intermediate treatment appears optimal." @default.
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- W423840912 date "2007-01-01" @default.
- W423840912 modified "2023-09-23" @default.
- W423840912 title "Influence of increasing total essential amino acids on nitrogen metabolism during caloric restriction in moderately overweight mature dogs" @default.
- W423840912 doi "https://doi.org/10.1096/fasebj.21.6.a743" @default.
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