Matches in SemOpenAlex for { <https://semopenalex.org/work/W4238420909> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W4238420909 endingPage "7" @default.
- W4238420909 startingPage "7" @default.
- W4238420909 abstract "In the present study, we report a selective electrochemical aptasensor for the ultrasensitive detection of an anti-inflammatory drug, ibuprofen (IBP). The proposed system was achieved by the modification of a glassy carbon electrode (GCE) with multiwalled carbon nanotubes/ionic liquid/chitosan (MWCNTs/IL/Chit) nanocomposite and the covalent immobilization of the IBP specific aptamer (Apt) onto the modified electrode surface followed by methylene blue (MB) intercalated onto the Apt as the electrochemical redox marker. Upon the incubation of the IBP as a target in the proposed aptasensor, the peak current of MB decreases due to the formation of the Apt-IBP complex and the displacement of MB from the immobilized Apt onto the modified electrode surface. The nanocomposite not only increases the electrode surface area and accelerate the electron transfer kinetics but also it provides a highly stable matrix to enhance the loading amount of the Apt DNA sequence. Through differential pulse voltammetry (DPV) experiments, it was found that the proposed aptasensor could detect the IBP with a linear range (70 pM up to 6 μM) and the detection limit (LOD) as low as 20 pM. The results showed that the aptasensor had good sensitivity, stability, reproducibility, and specificity to detect the IBP. The proposed aptasensor was successfully applied for measuring the IBP concentration in real samples. Based on our experiments we can say that the present method proposes new horizons for the development of other aptasensors for diagnostic application in biosensing." @default.
- W4238420909 created "2022-05-12" @default.
- W4238420909 date "1993-09-01" @default.
- W4238420909 modified "2023-10-17" @default.
- W4238420909 title "Aerospace conference proceedings published" @default.
- W4238420909 doi "https://doi.org/10.1016/0026-0657(93)90759-l" @default.
- W4238420909 hasPublicationYear "1993" @default.
- W4238420909 type Work @default.
- W4238420909 citedByCount "0" @default.
- W4238420909 crossrefType "journal-article" @default.
- W4238420909 hasConcept C10349863 @default.
- W4238420909 hasConcept C119128265 @default.
- W4238420909 hasConcept C127413603 @default.
- W4238420909 hasConcept C128972844 @default.
- W4238420909 hasConcept C147789679 @default.
- W4238420909 hasConcept C160756335 @default.
- W4238420909 hasConcept C171250308 @default.
- W4238420909 hasConcept C17525397 @default.
- W4238420909 hasConcept C185592680 @default.
- W4238420909 hasConcept C192562407 @default.
- W4238420909 hasConcept C2777869211 @default.
- W4238420909 hasConcept C2779525745 @default.
- W4238420909 hasConcept C42360764 @default.
- W4238420909 hasConcept C43617362 @default.
- W4238420909 hasConcept C513720949 @default.
- W4238420909 hasConcept C52859227 @default.
- W4238420909 hasConcept C54355233 @default.
- W4238420909 hasConcept C86803240 @default.
- W4238420909 hasConcept C92880739 @default.
- W4238420909 hasConceptScore W4238420909C10349863 @default.
- W4238420909 hasConceptScore W4238420909C119128265 @default.
- W4238420909 hasConceptScore W4238420909C127413603 @default.
- W4238420909 hasConceptScore W4238420909C128972844 @default.
- W4238420909 hasConceptScore W4238420909C147789679 @default.
- W4238420909 hasConceptScore W4238420909C160756335 @default.
- W4238420909 hasConceptScore W4238420909C171250308 @default.
- W4238420909 hasConceptScore W4238420909C17525397 @default.
- W4238420909 hasConceptScore W4238420909C185592680 @default.
- W4238420909 hasConceptScore W4238420909C192562407 @default.
- W4238420909 hasConceptScore W4238420909C2777869211 @default.
- W4238420909 hasConceptScore W4238420909C2779525745 @default.
- W4238420909 hasConceptScore W4238420909C42360764 @default.
- W4238420909 hasConceptScore W4238420909C43617362 @default.
- W4238420909 hasConceptScore W4238420909C513720949 @default.
- W4238420909 hasConceptScore W4238420909C52859227 @default.
- W4238420909 hasConceptScore W4238420909C54355233 @default.
- W4238420909 hasConceptScore W4238420909C86803240 @default.
- W4238420909 hasConceptScore W4238420909C92880739 @default.
- W4238420909 hasIssue "9" @default.
- W4238420909 hasLocation W42384209091 @default.
- W4238420909 hasOpenAccess W4238420909 @default.
- W4238420909 hasPrimaryLocation W42384209091 @default.
- W4238420909 hasRelatedWork W2003754443 @default.
- W4238420909 hasRelatedWork W2056549532 @default.
- W4238420909 hasRelatedWork W2153100473 @default.
- W4238420909 hasRelatedWork W2370941806 @default.
- W4238420909 hasRelatedWork W2371768113 @default.
- W4238420909 hasRelatedWork W2384171552 @default.
- W4238420909 hasRelatedWork W2414078896 @default.
- W4238420909 hasRelatedWork W3186615632 @default.
- W4238420909 hasRelatedWork W3209172720 @default.
- W4238420909 hasRelatedWork W4226189162 @default.
- W4238420909 hasVolume "48" @default.
- W4238420909 isParatext "false" @default.
- W4238420909 isRetracted "false" @default.
- W4238420909 workType "article" @default.