Matches in SemOpenAlex for { <https://semopenalex.org/work/W4238431392> ?p ?o ?g. }
- W4238431392 endingPage "2033" @default.
- W4238431392 startingPage "2025" @default.
- W4238431392 abstract "The SSA1 gene, one of the heat-inducible HSP70 genes in the yeast Saccharomyces cerevisiae, also displays a basal level of expression during logarithmic growth. Multiple sites related to the heat shock element (HSE) consensus sequence are present in the SSA1 promoter region (Slater and Craig, Mol. Cell. Biol. 7:1906-1916, 1987). One of the HSEs, HSE2, is important in the basal expression of SSA1 as well as in heat-inducible expression. A promoter containing a mutant HSE2 showed a fivefold-lower level of basal expression and altered kinetics of expression after heat shock. A series of deletion and point mutations led to identification of an upstream repression sequence (URS) which overlapped HSE2. A promoter containing a mutation in the URS showed an increased level of basal expression. A URS-binding activity was detected in yeast whole-cell extracts by a gel electrophoresis DNA-binding assay. The results reported in this paper indicate that basal expression of the SSA1 promoter is determined by both positive and negative elements and imply that the positively acting yeast heat shock factor HSF is responsible, at least in part, for the basal level of expression of SSA1." @default.
- W4238431392 created "2022-05-12" @default.
- W4238431392 creator A5023094153 @default.
- W4238431392 creator A5044904036 @default.
- W4238431392 date "1989-05-01" @default.
- W4238431392 modified "2023-09-29" @default.
- W4238431392 title "Positive and negative regulation of basal expression of a yeast HSP70 gene" @default.
- W4238431392 cites W1433025566 @default.
- W4238431392 cites W1532921349 @default.
- W4238431392 cites W1732882 @default.
- W4238431392 cites W1781717284 @default.
- W4238431392 cites W1895955548 @default.
- W4238431392 cites W1962269101 @default.
- W4238431392 cites W1964449641 @default.
- W4238431392 cites W1965267927 @default.
- W4238431392 cites W1973782344 @default.
- W4238431392 cites W1977388184 @default.
- W4238431392 cites W1979017960 @default.
- W4238431392 cites W1980014349 @default.
- W4238431392 cites W1987703174 @default.
- W4238431392 cites W1988198388 @default.
- W4238431392 cites W1995267722 @default.
- W4238431392 cites W2004563262 @default.
- W4238431392 cites W2005131012 @default.
- W4238431392 cites W2005383788 @default.
- W4238431392 cites W2009968835 @default.
- W4238431392 cites W2014914786 @default.
- W4238431392 cites W2019486354 @default.
- W4238431392 cites W2023482892 @default.
- W4238431392 cites W2024414544 @default.
- W4238431392 cites W2025450446 @default.
- W4238431392 cites W2036639970 @default.
- W4238431392 cites W2049481106 @default.
- W4238431392 cites W2054468433 @default.
- W4238431392 cites W2069235651 @default.
- W4238431392 cites W2070616628 @default.
- W4238431392 cites W2071769765 @default.
- W4238431392 cites W2074007751 @default.
- W4238431392 cites W2080269085 @default.
- W4238431392 cites W2081088219 @default.
- W4238431392 cites W2082205973 @default.
- W4238431392 cites W2091228527 @default.
- W4238431392 cites W2091288867 @default.
- W4238431392 cites W2117936243 @default.
- W4238431392 cites W2138639730 @default.
- W4238431392 cites W2159271990 @default.
- W4238431392 cites W2169058508 @default.
- W4238431392 cites W2888511473 @default.
- W4238431392 cites W4235592770 @default.
- W4238431392 cites W4246092406 @default.
- W4238431392 cites W4249988281 @default.
- W4238431392 cites W4293247451 @default.
- W4238431392 doi "https://doi.org/10.1128/mcb.9.5.2025-2033.1989" @default.
- W4238431392 hasPublicationYear "1989" @default.
- W4238431392 type Work @default.
- W4238431392 citedByCount "2" @default.
- W4238431392 countsByYear W42384313922023 @default.
- W4238431392 crossrefType "journal-article" @default.
- W4238431392 hasAuthorship W4238431392A5023094153 @default.
- W4238431392 hasAuthorship W4238431392A5044904036 @default.
- W4238431392 hasConcept C101762097 @default.
- W4238431392 hasConcept C104317684 @default.
- W4238431392 hasConcept C143065580 @default.
- W4238431392 hasConcept C150194340 @default.
- W4238431392 hasConcept C153911025 @default.
- W4238431392 hasConcept C176944494 @default.
- W4238431392 hasConcept C205260736 @default.
- W4238431392 hasConcept C21592294 @default.
- W4238431392 hasConcept C2777576037 @default.
- W4238431392 hasConcept C2779222958 @default.
- W4238431392 hasConcept C501734568 @default.
- W4238431392 hasConcept C54355233 @default.
- W4238431392 hasConcept C68991219 @default.
- W4238431392 hasConcept C86803240 @default.
- W4238431392 hasConceptScore W4238431392C101762097 @default.
- W4238431392 hasConceptScore W4238431392C104317684 @default.
- W4238431392 hasConceptScore W4238431392C143065580 @default.
- W4238431392 hasConceptScore W4238431392C150194340 @default.
- W4238431392 hasConceptScore W4238431392C153911025 @default.
- W4238431392 hasConceptScore W4238431392C176944494 @default.
- W4238431392 hasConceptScore W4238431392C205260736 @default.
- W4238431392 hasConceptScore W4238431392C21592294 @default.
- W4238431392 hasConceptScore W4238431392C2777576037 @default.
- W4238431392 hasConceptScore W4238431392C2779222958 @default.
- W4238431392 hasConceptScore W4238431392C501734568 @default.
- W4238431392 hasConceptScore W4238431392C54355233 @default.
- W4238431392 hasConceptScore W4238431392C68991219 @default.
- W4238431392 hasConceptScore W4238431392C86803240 @default.
- W4238431392 hasIssue "5" @default.
- W4238431392 hasLocation W42384313921 @default.
- W4238431392 hasOpenAccess W4238431392 @default.
- W4238431392 hasPrimaryLocation W42384313921 @default.
- W4238431392 hasRelatedWork W1826456176 @default.
- W4238431392 hasRelatedWork W1865915409 @default.
- W4238431392 hasRelatedWork W2002237446 @default.
- W4238431392 hasRelatedWork W2075471727 @default.
- W4238431392 hasRelatedWork W2134982307 @default.
- W4238431392 hasRelatedWork W2166892452 @default.