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• W4238505768 abstract "Childhood-onset systemic lupus erythematosus (SLE) is a subset of SLE with an onset before 18 years of age. Patients with early onset SLE tend to have a greater genetic component to their disease cause, more multisystemic involvement, and a more severe disease course, which includes greater risks for developing nephritis and end-stage kidney disease. Five- and 10-year mortality is lower than in adult-onset SLE. Although patient and renal survival have improved with advances in induction and maintenance immunosuppression , accumulation of irreversible damage is common. Cardiovascular and infectious complications are frequent, as are relapses during adolescence and the transition to adulthood." @default.
• W4238505768 created "2022-05-12" @default.
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• W4238505768 date "2019-02-01" @default.
• W4238505768 modified "2023-10-14" @default.
• W4238505768 title "Lupus Nephritis" @default.
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• W4238505768 doi "https://doi.org/10.1016/j.pcl.2018.08.007" @default.
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