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- W4238670852 abstract "We report two cases of primary inferior vena cava (IVC) leiomyosarcoma resection, one confined to the infrarenal IVC and the other extending to the suprahepatic IVC. Both patients were females in their late 50s who presented with abdominal pain and malaise and without evidence of metastases. The first patient was initially diagnosed with a retroperitoneal sarcoma of unknown origin. Vascular surgery was consulted intra-operatively when it became evident that the infrarenal IVC was primarily involved. The tumor in the second patient involved not only the infrarenal IVC but extended cephalad to the suprahepatic IVC. A review of this rare tumor and intraoperative photos detailing the operative strategies will be presented. The first patient required proximal clamping of the IVC immediately below the renal veins. In the second patient, intrapericardial IVC clamping was required along with clamping of the portal triad and reimplantation of the right renal vein into the graft. After tumor and IVC excision, both patients underwent concomitant interposition polytetrafluoroethylene (PTFE) graft replacement. Primary tumors of the inferior vena cava (IVC) are rare, with leiomyosarcoma (LMS) representing the vast majority (95%). Greater than 50% of all vascular LMSs occur in the IVC. Prognosis is often poor due to advanced stage at diagnosis owing to a slow growth pattern. There is no proven role for adjuvant treatment and recurrence is common. Surgical excision of the tumor and affected IVC is the only treatment shown to improve survival. Reconstruction of the IVC and other involved vessels is often required." @default.
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- W4238670852 date "2009-10-01" @default.
- W4238670852 modified "2023-09-26" @default.
- W4238670852 title "Primary Leiomyosarcoma of the Inferior Vena Cava: Reports of Infrarenal and Suprahepatic Caval Involvement" @default.
- W4238670852 doi "https://doi.org/10.1016/j.jvs.2009.07.059" @default.
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