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- W4238693757 abstract "The means for chemical contraception are now available, with various estrogen progestin regimes. Considerable clinical and biological effort is devoted to find new and more convenient means of employing these hormonal agents. The success achieved with post coitally administered estrogens may lead to a post coital pill. In the female, for example, it is possible to prevent ovulation, sperm capacitation, and transport of that sperm to the oviduct, penetration of the egg by sperm, division of the fertilized egg, transport of the egg to the uterus, or even nidation. The developmental process of the male germ cell from the spermatogonium to a mature sperm cell also appears to offer numerous points of attack. Despite this, the only practical means of chemical contraception as presently available consists of estrogen progestin type of oral contraceptives. Though much effort has been expended in the search for some means of contraception that does not involve the pituitary, such an agent has not yet been found. Despite a large amount of both chemical and biological work on compounds that may be loosely termed estrogen antagonists, no notice of clinical success of such an agent has as yet appeared. An ideal agent for achieving contraception would be a drug that completely bypasses the endocrine system; this breakthrough is still to come." @default.
- W4238693757 created "2022-05-12" @default.
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- W4238693757 date "1967-01-01" @default.
- W4238693757 modified "2023-09-23" @default.
- W4238693757 title "Chapter 19. Reproduction" @default.
- W4238693757 doi "https://doi.org/10.1016/s0065-7743(08)60263-8" @default.
- W4238693757 hasPublicationYear "1967" @default.
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