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- W4238753362 abstract "Over 50 million people worldwide live with the consequences of brain and spinal cord injury. Unfortunately, nervous system tissue is very fragile and its protection by the bones of skull and vertebral column is insufficient to withstand the forces encountered in motor vehicle accidents or during contact sports. Though our understanding of primary and secondary nervous system injury is excellent, effective therapeutics to enhance a patient’s recovery are largely absent. At best, rehabilitation and robotic assist devices make disease more manageable. The major hurdles are the inability of most neurons to replicate after injury, and the active, multipronged suppression of axonal regeneration by myelin-associated molecules and glial scars. Exciting progress has been made in overcoming these hurdles in preclinical studies, and clinical trials show promise with the implantation of autologous stem cells. Increased public awareness of the danger associated with repeated mild injuries in sporting activities is having positive effects on the use of protective measures in athletics." @default.
- W4238753362 created "2022-05-12" @default.
- W4238753362 creator A5088300774 @default.
- W4238753362 date "2021-01-01" @default.
- W4238753362 modified "2023-10-16" @default.
- W4238753362 title "Central Nervous System Trauma" @default.
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- W4238753362 doi "https://doi.org/10.1016/b978-0-12-821228-8.00002-0" @default.
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