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- W4238754008 abstract "In Brief OBJECTIVE Preeclampsia shares many risk factors and pathophysiologic features with coronary heart disease. We studied whether, like atherosclerosis, preeclampsia is related to seroprevalence of immunoglobulin (Ig) G antibodies to Chlamydia pneumoniae. METHODS Cross-sectional comparisons were made for 37 women with preeclampsia and 37 women with normal pregnancies at term. In these two groups, antibody titers for IgG, IgM, and IgA seroprevalence to C pneumoniae and IgG to Chlamydia trachomatis and Chlamydia psittaci were compared. RESULTS Immunoglobulin G antibodies to C pneumoniae at a titer of at least 1:16 were more common in women with preeclampsia (25 of 37) than in women without (15 of 37) (odds ratio 3.1; 95% confidence interval 1.2, 7.9). There were no significant differences in the seroprevalence of IgA or IgM antibodies to C pneumoniae. Women with preeclampsia were also no more likely to have IgG antibodies to C trachomatis or C psittaci. CONCLUSION Women with preeclampsia had an increased IgG seroprevalence to C pneumoniae but not to C trachomatis or C psittaci. These preliminary data suggest a specific association between infection with C pneumoniae and preeclampsia. As compared with women with normal, term pregnancies, women with preeclampsia have an increased seroprevalence of immunoglobulin G to Chlamydia pneumoniae." @default.
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- W4238754008 date "2003-02-01" @default.
- W4238754008 modified "2023-10-17" @default.
- W4238754008 title "Seroprevalence of Antibodies to Chlamydia pneumoniae in Women With Preeclampsia" @default.
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- W4238754008 doi "https://doi.org/10.1097/00006250-200302000-00005" @default.
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