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- W4238762145 abstract "Acute pancreatitis is a clinical syndrome characterized by injury to the pancreas that invokes an inflammatory response ranging in severity and leading to a range of complications. The role of specific genetic variations in both the susceptibility to pancreatic injury and the response to injury is increasingly recognized. This chapter highlights several of these key genetic variants, including prototype susceptibility genes, such as PRSS1, CFTR, and SPINK1. The increasingly recognized role of disease-modifying genes for proinflammatory cytokines such as those encoding interleukin 8 (IL-8), monocyte chemotactic protein-1 (MCP-1), and tumor necrosis factor α (TNF-α) is also addressed. More research is needed to integrate this and future information into useful clinical strategies to manage acute pancreatitis and prevent its complications." @default.
- W4238762145 created "2022-05-12" @default.
- W4238762145 creator A5052922833 @default.
- W4238762145 creator A5066372102 @default.
- W4238762145 date "2018-02-12" @default.
- W4238762145 modified "2023-10-14" @default.
- W4238762145 title "Genetic Factors in Acute Pancreatitis" @default.
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- W4238762145 doi "https://doi.org/10.1002/9781119188421.ch15" @default.
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