Matches in SemOpenAlex for { <https://semopenalex.org/work/W4238991009> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W4238991009 endingPage "8549" @default.
- W4238991009 startingPage "8549" @default.
- W4238991009 abstract "8549 Background: The radiographic detection of the small pulmonary nodule during the initial metastatic workup of the pediatric oncology patient presents a significant clinical dilemma. The outcome of the decision of whether the nodule is malignant or benign often affects decisions regarding treatment, protocol enrollment, and assessment of prognosis. The incidence of this clinical situation in the era of helical computed tomography (CT) is unknown and practice guidelines pertaining to the pretherapy evaluation of the small pulmonary nodule are lacking. Methods: We performed a retrospective review of initial lung CT reports of 181 consecutive pediatric patients referred to our hospital for the primary treatment of bone or soft-tissue sarcomas from 1999–2003. The frequency, number, size, location and characteristics of nodules were documented. These lung CT findings were correlated with the histologic conclusions from lung biopsy and/or clinical outcome. Results: : Pulmonary nodules were found on CT evaluation in 57 (31%) of patients. In approximately half of these patients, the largest nodule was less than or equal to 10 mm diameter. Twenty-two patients were coded as having pulmonary metastatic disease by the primary oncologist. Four of these patients underwent a lung biopsy to histologically confirm pulmonary metastasis. The remaining 18 patients were determined to have pulmonary metastasis without further intervention. Of the 35 patients who were coded as not having pulmonary metastasis, 12 had lung biopsies showing normal lung or granulomatous disease. Patients with osteosarcoma were more likely to have an invasive procedure (p=0.010), but size, number of nodules, and presence of calcifications were not predicative (p>0.36) of those going to biopsy. Conclusions: Our findings confirm that the finding of a small pulmonary nodule during the initial workup of pediatric patients with sarcoma presents a common clinical scenario and highlights the need for a systematic approach to its evaluation. A proposal to study this problem will be offered. No significant financial relationships to disclose." @default.
- W4238991009 created "2022-05-12" @default.
- W4238991009 creator A5031403389 @default.
- W4238991009 creator A5043103971 @default.
- W4238991009 creator A5045180889 @default.
- W4238991009 creator A5049537528 @default.
- W4238991009 creator A5077159490 @default.
- W4238991009 date "2004-07-15" @default.
- W4238991009 modified "2023-09-26" @default.
- W4238991009 title "Pulmonary nodules in the initial evaluation of pediatric patients with bone and soft-tissue sarcoma" @default.
- W4238991009 doi "https://doi.org/10.1200/jco.2004.22.14_suppl.8549" @default.
- W4238991009 hasPublicationYear "2004" @default.
- W4238991009 type Work @default.
- W4238991009 citedByCount "0" @default.
- W4238991009 crossrefType "journal-article" @default.
- W4238991009 hasAuthorship W4238991009A5031403389 @default.
- W4238991009 hasAuthorship W4238991009A5043103971 @default.
- W4238991009 hasAuthorship W4238991009A5045180889 @default.
- W4238991009 hasAuthorship W4238991009A5049537528 @default.
- W4238991009 hasAuthorship W4238991009A5077159490 @default.
- W4238991009 hasConcept C121608353 @default.
- W4238991009 hasConcept C126322002 @default.
- W4238991009 hasConcept C126838900 @default.
- W4238991009 hasConcept C136948725 @default.
- W4238991009 hasConcept C142724271 @default.
- W4238991009 hasConcept C151730666 @default.
- W4238991009 hasConcept C2775934546 @default.
- W4238991009 hasConcept C2776731575 @default.
- W4238991009 hasConcept C2777714996 @default.
- W4238991009 hasConcept C2778256501 @default.
- W4238991009 hasConcept C2779013556 @default.
- W4238991009 hasConcept C2780244788 @default.
- W4238991009 hasConcept C544519230 @default.
- W4238991009 hasConcept C71924100 @default.
- W4238991009 hasConcept C86803240 @default.
- W4238991009 hasConceptScore W4238991009C121608353 @default.
- W4238991009 hasConceptScore W4238991009C126322002 @default.
- W4238991009 hasConceptScore W4238991009C126838900 @default.
- W4238991009 hasConceptScore W4238991009C136948725 @default.
- W4238991009 hasConceptScore W4238991009C142724271 @default.
- W4238991009 hasConceptScore W4238991009C151730666 @default.
- W4238991009 hasConceptScore W4238991009C2775934546 @default.
- W4238991009 hasConceptScore W4238991009C2776731575 @default.
- W4238991009 hasConceptScore W4238991009C2777714996 @default.
- W4238991009 hasConceptScore W4238991009C2778256501 @default.
- W4238991009 hasConceptScore W4238991009C2779013556 @default.
- W4238991009 hasConceptScore W4238991009C2780244788 @default.
- W4238991009 hasConceptScore W4238991009C544519230 @default.
- W4238991009 hasConceptScore W4238991009C71924100 @default.
- W4238991009 hasConceptScore W4238991009C86803240 @default.
- W4238991009 hasIssue "14_suppl" @default.
- W4238991009 hasLocation W42389910091 @default.
- W4238991009 hasOpenAccess W4238991009 @default.
- W4238991009 hasPrimaryLocation W42389910091 @default.
- W4238991009 hasRelatedWork W1980761243 @default.
- W4238991009 hasRelatedWork W2010920639 @default.
- W4238991009 hasRelatedWork W2047291195 @default.
- W4238991009 hasRelatedWork W2127354531 @default.
- W4238991009 hasRelatedWork W2161254563 @default.
- W4238991009 hasRelatedWork W2357577286 @default.
- W4238991009 hasRelatedWork W2416760686 @default.
- W4238991009 hasRelatedWork W2594735789 @default.
- W4238991009 hasRelatedWork W2789892372 @default.
- W4238991009 hasRelatedWork W3187267698 @default.
- W4238991009 hasVolume "22" @default.
- W4238991009 isParatext "false" @default.
- W4238991009 isRetracted "false" @default.
- W4238991009 workType "article" @default.