FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4238996218> ?p ?o ?g. }

• W4238996218 endingPage "280" @default.
• W4238996218 startingPage "273" @default.
• W4238996218 abstract "Nicotinic acid adenine dinucleotide phosphate (NAADP) is a recently described Ca2+ mobilizing messenger. First described in the sea urchin egg, it has been shown to mobilize Ca2+ from intracellular stores. It is a remarkably potent molecule, and recent reports show that its cellular levels change in response to a variety of agonists confirming its role as a Ca2+ mobilizing messenger. In many cases NAADP interacts with other Ca2+ mobilizing messengers such as inositol 1,4,5 trisphosphate (IP3 and cyclic adenosine diphosphate ribose (cADPR) in shaping cytosolic Ca2+ signals. What is not clear is the molecular nature of the NAADP-sensitive Ca2+ release mechanism and its sub-cellular localization. In this review we focus on the recent progress made in sea urchin eggs, which indicates that NAADP activates a novel Ca2+ release channel distinct from the relatively well-characterized IP3 and ryanodine receptors. Furthermore, in the sea urchin egg, the NAADP-sensitive store appears to be separate from the endoplasmic reticulum (ER) and is most likely an acidic store. These findings have also been reinforced by similar findings by some in mammalian cells. Finally, we discuss ongoing strategies to characterise NAADP-binding proteins which will greatly enhance our understanding of NAADP-mediated Ca2+ signalling, and lead to the development of more selective tools to probe the role of this messenger." @default.
• W4238996218 created "2022-05-12" @default.
• W4238996218 creator A5026573711 @default.
• W4238996218 creator A5026968435 @default.
• W4238996218 date "2005-09-01" @default.
• W4238996218 modified "2023-09-26" @default.
• W4238996218 title "NAADP receptors" @default.
• W4238996218 cites W1528977425 @default.
• W4238996218 cites W1538340522 @default.
• W4238996218 cites W1615545200 @default.
• W4238996218 cites W1853732393 @default.
• W4238996218 cites W1946056901 @default.
• W4238996218 cites W1963403501 @default.
• W4238996218 cites W1963869670 @default.
• W4238996218 cites W1967329828 @default.
• W4238996218 cites W1967940275 @default.
• W4238996218 cites W1969637387 @default.
• W4238996218 cites W1971881864 @default.
• W4238996218 cites W1975992025 @default.
• W4238996218 cites W1976269779 @default.
• W4238996218 cites W1980615710 @default.
• W4238996218 cites W1990863061 @default.
• W4238996218 cites W1994577418 @default.
• W4238996218 cites W1997119596 @default.
• W4238996218 cites W1997223430 @default.
• W4238996218 cites W2001695130 @default.
• W4238996218 cites W2010410469 @default.
• W4238996218 cites W2012467728 @default.
• W4238996218 cites W2026571586 @default.
• W4238996218 cites W2039043166 @default.
• W4238996218 cites W2041740826 @default.
• W4238996218 cites W2055221223 @default.
• W4238996218 cites W2061962091 @default.
• W4238996218 cites W2063327869 @default.
• W4238996218 cites W2063348606 @default.
• W4238996218 cites W2064791032 @default.
• W4238996218 cites W2065368005 @default.
• W4238996218 cites W2066342307 @default.
• W4238996218 cites W2069945478 @default.
• W4238996218 cites W2077080379 @default.
• W4238996218 cites W2078391920 @default.
• W4238996218 cites W2078654071 @default.
• W4238996218 cites W2082625926 @default.
• W4238996218 cites W2086134353 @default.
• W4238996218 cites W2087510642 @default.
• W4238996218 cites W2088421990 @default.
• W4238996218 cites W2092613581 @default.
• W4238996218 cites W2092715930 @default.
• W4238996218 cites W2093144498 @default.
• W4238996218 cites W2093716452 @default.
• W4238996218 cites W2094112331 @default.
• W4238996218 cites W2103322177 @default.
• W4238996218 cites W2122496105 @default.
• W4238996218 cites W2128498401 @default.
• W4238996218 cites W2130615219 @default.
• W4238996218 cites W2133772521 @default.
• W4238996218 cites W2136392779 @default.
• W4238996218 cites W2139034255 @default.
• W4238996218 cites W2144287928 @default.
• W4238996218 cites W2144344199 @default.
• W4238996218 cites W2146447679 @default.
• W4238996218 cites W2161432643 @default.
• W4238996218 cites W2162006028 @default.
• W4238996218 cites W2163760215 @default.
• W4238996218 cites W2164715751 @default.
• W4238996218 cites W2409899947 @default.
• W4238996218 cites W4211044652 @default.
• W4238996218 cites W4238398689 @default.
• W4238996218 doi "https://doi.org/10.1016/j.ceca.2005.06.031" @default.
• W4238996218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16111747" @default.
• W4238996218 hasPublicationYear "2005" @default.
• W4238996218 type Work @default.
• W4238996218 citedByCount "47" @default.
• W4238996218 countsByYear W42389962182012 @default.
• W4238996218 countsByYear W42389962182013 @default.
• W4238996218 countsByYear W42389962182014 @default.
• W4238996218 countsByYear W42389962182015 @default.
• W4238996218 countsByYear W42389962182016 @default.
• W4238996218 countsByYear W42389962182017 @default.
• W4238996218 countsByYear W42389962182018 @default.
• W4238996218 countsByYear W42389962182019 @default.
• W4238996218 countsByYear W42389962182021 @default.
• W4238996218 countsByYear W42389962182022 @default.
• W4238996218 crossrefType "journal-article" @default.
• W4238996218 hasAuthorship W4238996218A5026573711 @default.
• W4238996218 hasAuthorship W4238996218A5026968435 @default.
• W4238996218 hasConcept C10205521 @default.
• W4238996218 hasConcept C113217602 @default.
• W4238996218 hasConcept C152624196 @default.
• W4238996218 hasConcept C158617107 @default.
• W4238996218 hasConcept C159912055 @default.
• W4238996218 hasConcept C163235415 @default.
• W4238996218 hasConcept C170493617 @default.
• W4238996218 hasConcept C181199279 @default.
• W4238996218 hasConcept C185592680 @default.
• W4238996218 hasConcept C201571599 @default.
• W4238996218 hasConcept C2776908312 @default.
• W4238996218 hasConcept C2777336126 @default.

• next