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- W4239077573 abstract "Background : Human saliva contains approximately 700 bacterial species but the relatedness of salivary bacteria from parents to adult children is not investigated in humans. The objectives were to investigate the entirety of salivary bacterial DNA profiles and whether and how families share these profiles and also compare these communities between adult parent-off-spring pairs using 16S rRNA gene amplicon sequencing. Results: The most abundant phyla in two separate families were Firmicutes, Bacteroidetes, Proteobacteria, Fusobacteria and Actinobacteria . Family ties explained 13 % of the variance between individuals’ bacterial communities (R 2 =0.13; P=0.001). Mothers shared more OTUs with their adult children compared to fathers, but this linkage seemed to be weaker in the family with older adult children. We identified 29 differentially abundant genus level OTUs (FDR < 0.05) between the families, which accounted for 31 % of the total identified genus level OTUs Conclusions: Our results indicate that adult family members share bacterial communities and adult children were more similar to mothers than fathers. Our results suggest implicitly that a similarity in oral microbiome between parent-child pairs is present, but may change over time." @default.
- W4239077573 created "2022-05-12" @default.
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- W4239077573 date "2019-03-04" @default.
- W4239077573 modified "2023-10-12" @default.
- W4239077573 title "Similarity of salivary microbiome in parents and adult children" @default.
- W4239077573 doi "https://doi.org/10.7287/peerj.preprints.27565v1" @default.
- W4239077573 hasPublicationYear "2019" @default.
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