Matches in SemOpenAlex for { <https://semopenalex.org/work/W4239100384> ?p ?o ?g. }
- W4239100384 endingPage "12844" @default.
- W4239100384 startingPage "12840" @default.
- W4239100384 abstract "Abstract A highly stereoselective three‐component C(sp 2 )−H bond addition across alkene and polarized π‐bonds is reported for which Co III catalysis was shown to be much more effective than Rh III . The reaction proceeds at ambient temperature with both aryl and alkyl enones employed as efficient coupling partners. Moreover, the reaction exhibits extremely broad scope with respect to the aldehyde input; electron rich and poor aromatic, alkenyl, and branched and unbranched alkyl aldehydes all couple in good yield and with high diastereoselectivity. Multiple directing groups participate in this transformation, including pyrazole, pyridine, and imine functional groups. Both aromatic and alkenyl C(sp 2 )−H bonds undergo the three‐component addition cascade, and the alkenyl addition product can readily be converted into diastereomerically pure five‐membered lactones. Additionally, the first asymmetric reactions with Co III ‐catalyzed C−H functionalization are demonstrated with three‐component C−H bond addition cascades employing N‐tert ‐butanesulfinyl imines. These examples represent the first transition metal catalyzed C−H bond additions to N‐tert ‐butanesulfinyl imines, which are versatile and extensively used intermediates for the asymmetric synthesis of amines." @default.
- W4239100384 created "2022-05-12" @default.
- W4239100384 creator A5012406363 @default.
- W4239100384 creator A5023344916 @default.
- W4239100384 creator A5084347710 @default.
- W4239100384 date "2016-06-15" @default.
- W4239100384 modified "2023-10-07" @default.
- W4239100384 title "Highly Stereoselective Cobalt(III)‐Catalyzed Three‐Component C−H Bond Addition Cascade" @default.
- W4239100384 cites W1976613964 @default.
- W4239100384 cites W1989688131 @default.
- W4239100384 cites W2025255412 @default.
- W4239100384 cites W2028136544 @default.
- W4239100384 cites W2028885535 @default.
- W4239100384 cites W2030768159 @default.
- W4239100384 cites W2033847517 @default.
- W4239100384 cites W2036044855 @default.
- W4239100384 cites W2037520525 @default.
- W4239100384 cites W2056537097 @default.
- W4239100384 cites W2061640787 @default.
- W4239100384 cites W2062799381 @default.
- W4239100384 cites W2067433167 @default.
- W4239100384 cites W2068749447 @default.
- W4239100384 cites W2069483854 @default.
- W4239100384 cites W2075813623 @default.
- W4239100384 cites W2085870789 @default.
- W4239100384 cites W2097186155 @default.
- W4239100384 cites W2104742517 @default.
- W4239100384 cites W2109086421 @default.
- W4239100384 cites W2110545008 @default.
- W4239100384 cites W2111890770 @default.
- W4239100384 cites W2113278931 @default.
- W4239100384 cites W2117781368 @default.
- W4239100384 cites W2117915009 @default.
- W4239100384 cites W2121053702 @default.
- W4239100384 cites W2123812009 @default.
- W4239100384 cites W2125663031 @default.
- W4239100384 cites W2126420609 @default.
- W4239100384 cites W2143157517 @default.
- W4239100384 cites W2143356381 @default.
- W4239100384 cites W2150911938 @default.
- W4239100384 cites W2152392262 @default.
- W4239100384 cites W2161166687 @default.
- W4239100384 cites W2165822455 @default.
- W4239100384 cites W2174180050 @default.
- W4239100384 cites W2187855276 @default.
- W4239100384 cites W2208888727 @default.
- W4239100384 cites W2260120853 @default.
- W4239100384 cites W2266192373 @default.
- W4239100384 cites W2270616085 @default.
- W4239100384 cites W2273835029 @default.
- W4239100384 cites W2277315257 @default.
- W4239100384 cites W2285593887 @default.
- W4239100384 cites W2285749062 @default.
- W4239100384 cites W2288863861 @default.
- W4239100384 cites W2289138241 @default.
- W4239100384 cites W2292071740 @default.
- W4239100384 cites W2295264180 @default.
- W4239100384 cites W2297057104 @default.
- W4239100384 cites W2303760094 @default.
- W4239100384 cites W2309124348 @default.
- W4239100384 cites W2313171562 @default.
- W4239100384 cites W2314176890 @default.
- W4239100384 cites W2319250038 @default.
- W4239100384 cites W2321928492 @default.
- W4239100384 cites W2330374176 @default.
- W4239100384 cites W2331452414 @default.
- W4239100384 cites W2331468909 @default.
- W4239100384 cites W2460846234 @default.
- W4239100384 cites W2949636302 @default.
- W4239100384 cites W2951445248 @default.
- W4239100384 cites W2951786162 @default.
- W4239100384 cites W2952426984 @default.
- W4239100384 cites W4230158382 @default.
- W4239100384 cites W4230987817 @default.
- W4239100384 cites W4241475748 @default.
- W4239100384 cites W4246333403 @default.
- W4239100384 cites W4250150671 @default.
- W4239100384 cites W4250663340 @default.
- W4239100384 cites W4252115228 @default.
- W4239100384 doi "https://doi.org/10.1002/ange.201603831" @default.
- W4239100384 hasPublicationYear "2016" @default.
- W4239100384 type Work @default.
- W4239100384 citedByCount "46" @default.
- W4239100384 countsByYear W42391003842016 @default.
- W4239100384 countsByYear W42391003842017 @default.
- W4239100384 countsByYear W42391003842018 @default.
- W4239100384 countsByYear W42391003842019 @default.
- W4239100384 countsByYear W42391003842020 @default.
- W4239100384 countsByYear W42391003842021 @default.
- W4239100384 countsByYear W42391003842022 @default.
- W4239100384 crossrefType "journal-article" @default.
- W4239100384 hasAuthorship W4239100384A5012406363 @default.
- W4239100384 hasAuthorship W4239100384A5023344916 @default.
- W4239100384 hasAuthorship W4239100384A5084347710 @default.
- W4239100384 hasConcept C155647269 @default.
- W4239100384 hasConcept C161790260 @default.
- W4239100384 hasConcept C178790620 @default.
- W4239100384 hasConcept C181647583 @default.