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- W4239321185 abstract "Muscular dystrophy is a heterogeneous group of neuromuscular disorders that manifests as progressive muscle weakness, muscle wasting and, in many cases, death. Although there has been enormous progress in the molecular understanding of muscular dystrophy, there is still no cure. There are, however, several different therapeutic options under investigation, including adult-derived stem cell transplantation. Encouraging and pioneering experiments in mouse models for Duchenne’s muscular dystrophy (DMD) demonstrated that myoblasts could be transplanted into dystrophic muscle; these myoblasts repaired a small proportion of damaged myofibres. Subsequent work has been devoted to optimisation of this technique. In doing so, a number of adult-derived stem cells have been isolated, characterised and used in promising animal transplantation experiments. Further research is ongoing, and is clearly necessary to make this therapy a viable treatment option for patients with muscular dystrophy." @default.
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- W4239321185 date "2004-01-01" @default.
- W4239321185 modified "2023-09-26" @default.
- W4239321185 title "Stem cell therapy for muscular dystrophy" @default.
- W4239321185 doi "https://doi.org/10.1517/eobt.4.1.1.25257" @default.
- W4239321185 hasPublicationYear "2004" @default.
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